Increased expression of stemness genes and in women with ovarian endometriosis versus normal endometrium: A case-control study.

Background: Endometriosis is a common, chronic inflammatory disease which is defined as an overgrowth of endometrial tissue outside the uterine cavity. The etiology of this disease is complex and multifactorial but there is a strong evidence that supports the presence of endometrial stem cells and their possible involvement in endometriosis.

Objective: In this study, we analyzed the mRNA expression of stemness gene and reconsidered three other stemness genes in women with endometriosis compared to normal endometrium.