Publications by authors named "Fasil Aklilu"

Article Synopsis
  • Peste des Petits Ruminants (PPR) is a viral disease affecting primarily goats and sheep, with some controversy around its impact on atypical hosts like cattle, warranting investigation into its progression in both species.
  • The study involved 32 animals (16 goats and 16 cattle) inoculated with a specific PPR virus strain, leading to significant clinical differences: goats showed typical symptoms and earlier virus detection than cattle, which displayed milder signs.
  • Findings emphasize the need for further comparative pathology studies to enhance understanding of PPR virus dynamics and potential transmission pathways, which could be crucial for controlling outbreaks.
View Article and Find Full Text PDF

Peste des petits ruminants virus (PPRV) is a multi-host pathogen with sheep and goats as main hosts. To investigate the role of cattle in the epidemiology of PPR, we simulated conditions similar to East African zero-grazing husbandry practices in a series of trials with local Zebu cattle (Bos taurus indicus) co-housed with goats (Capra aegagrus hircus). Furthermore, we developed a mathematical model to assess the impact of PPRV-transmission from cattle to goats.

View Article and Find Full Text PDF

This report describes the complete genome sequence of a peste des petits ruminants virus (PPRV) isolate from Ethiopia in 2014. The strain (PPRV/Ethiopia/Habru/2014), which showed a normal virulence and relatively low morbidity in the field, belongs to the North African subclade of Lineage IV.

View Article and Find Full Text PDF

Peste des petits ruminants (PPR) is one of the most important transboundary diseases of small ruminants. In this study, nasal and oral swabs ( = 24) were collected from sheep ( = 7) and goats ( = 17) with clinical signs in southern Ethiopia in March 2020. PPR virus was isolated on Vero dog cells expressing the signaling lymphocyte activation molecule (VDS) and screened using RT-qPCR.

View Article and Find Full Text PDF