The association between -13 rs478927 gene polymorphism and dental caries susceptibility in children with mixed dentition from Birjand, Iran: A case-control study.

Background And Aims: Gene polymorphisms are responsible for at least part of the variation in caries susceptibility despite similar environmental factors. Genes involved in enamel formation like matrix metalloproteinase-13 () may participate in caries process. The aim was to investigate the association between rs478927 polymorphism and caries susceptibility in 6-years-old children from Birjand, Iran.