The effects of L-carnitine-loaded solid lipid nanoparticles on performance, antioxidant parameters, and expression of genes associated with cholesterol metabolism in laying hens.

The purpose of this study was to investigate the production performance, antioxidant parameters, egg yolk cholesterol content, and expression of genes related to cholesterol metabolism in laying hens fed L-carnitine (LC) and L-carnitine-loaded solid lipid nanoparticles (LC-SLNs). A total of 350 Hy-Line (w-36) laying hens at 50 wk of age (1520.0 ± 0.

Protective effect of l-carnitine-loaded solid lipid nanoparticles against HO-induced genotoxicity and apoptosis.

L-carnitine (LC) is a highly water-soluble compound involved in the β-oxidation of lipids and transportation of long-chain fatty acids across the membrane of mitochondria. However, the higher hydrophilicity of LC limits its free diffusion across the bilayer lipid membrane of intestinal epithelium in oral administration, decreasing oral bioavailability. Drug delivery with nanoparticles enhances cargo bioavailability and cellular uptake and improves therapeutic outcomes while decreasing unwanted side effects.

Stimulatory effects of nano-selenium and conjugated linoleic acid ‎ on antioxidant activity, trace minerals, and gene expression response of growing male Moghani lambs.

Sheep keepers need suitable strategies to improve animal immunity and the quality of their products. This study was aimed to evaluate the effect of nano-selenium (nano-Se) and conjugated linoleic acid (CLA) on an antioxidant statue, trace minerals, and mRNA expression of glutathione peroxidase 1 (GPX1) and selenoprotein W1 (SEPW1) genes in the liver and peroxisome proliferator-activated receptor-gamma (PPARγ) and stearoyl COA desaturase 1 (SCD1) genes in fat- tail of male Moghani lambs. Thirty male Moghani lambs, three months old and average weight 30.

Effects of inclusion of corn gluten feed in dairy rations on dry matter intake, milk yield, milk components, and ruminal fermentation parameters: a meta-analysis.

Corn gluten feed (CGF) is a co-product of wet milling that can replace energy or fiber ingredients in dairy cow rations. The present meta-analysis examines how inclusion of CGF can affect dry matter intake (DMI), milk yield (MY), milk components, and ruminal fermentation parameters. A literature search was conducted to identify papers published from 1990 to 2018.

Environmental efficiency of Saccharomyces cerevisiae on methane production in dairy and beef cattle via a meta-analysis.

The objective of the present study is to examine the effect of yeast (Saccharomyces cerevisiae) on reduction of methane (CH) production in dairy and beef cattle using meta-analytic methods. After compilation of relevant scientific publications available from the literature between 1990 and 2016, and applying exclusion and inclusion criteria, meta-analyses of data from dairy and beef cattle were applied for the pooled dataset or for each animal category (dairy or beef). The results of meta-analysis of all three datasets (all cattle, dairy cattle, or beef cattle) suggested that effect size of yeast either on daily CH production or on CH production per dry matter intake (CH/DMI) was not significant.