Assessment of Hepatic Profile in Acquired Aplastic Anemia: An Experience From Pakistan.

Introduction:  Aplastic anemia (AA) is characterized by pancytopenia and hypocellular marrow in the absence of an abnormal infiltrate or increase in reticulin fibrosis. The diagnosis of AA is challenging at times due to decreased cellularity and overlapping morphological features with other bone marrow failure syndromes. Hepatitis-associated aplastic anemia (HAAA) is a rare variant in which patients typically present with jaundice and hepatitis followed by pancytopenia almost within 6 months.

The Outcome of Hodgkin Lymphoma With Reference to Prognostic Markers.

Objectives: This study aimed to determine the impact of prognostic markers on the outcomes of Hodgkin lymphoma.

Methods: It is a cross-sectional, single-center study. A total of 60 patients diagnosed with Hodgkin lymphoma were recruited for the study over five years between 2016 to 2020.

Frequency of Intron 22 Inversion in Severe Hemophilia A Patients.

Objective: The aim of our study was to find the frequency of Intron 22 inversion (Inv22) in severe hemophilia A (HA) patients and to evaluate the association between Inv22 and FVIII inhibitor formation.

Method: Data analysis was carried out on IBM SPSS Statistics Version 23.00 (IBM Corp, Armonk, NY).

Frequency of Extended Red Cell Antigen Phenotype Among Patients of Hematological Diseases: A Single Center Study.

Background Alloimmunization of erythrocytes is a major problem in patients with hematological diseases that require frequent blood transfusions. Matching of extended red cell antigens of Kell, MNS, Kidd, and Duffy can decrease the risk of alloimmunization. Hence, in this study, the frequencies of the extended red cell phenotypes were explored.

Frequency of Specific and Non-specific Inhibitors in Haemophilia A Patients.

Objective: To determine the frequency of specific and non-specific inhibitors in haemophilia A patients.

Study Design: This is a cross-sectional study.

Patients And Methods: A total of 150 male haemophilia A patients were included in this cross-sectional study at the National Institute of Blood Diseases and Bone Marrow Transplant (NIBD), Karachi, Pakistan, from September 2019 to January 2022.

The Frequency of Rh Phenotype and Its Probable Genotype.

Aims And Objectives: Our goal is to disseminate data on the distribution pattern of Rh antigen, its phenotypes, and the likely genotypes of these genetic variants in the Pakistani population.

Methodology: This study was a cross-sectional research project. Patients' demographic statistics, such as age and gender, were gathered from their medical information.