Varicocele Time-dependently Affects DNA Integrity of Sperm Cells: Evidence for Lower In vitro Fertilization Rate in Varicocele-positive Rats.

Background: We designed this study to clarify how varicocele can time-dependently affect sperm morphological parameters and DNA integrity. In this study, we intend to estimate the effect of various periods of varicocele on the in vitro fertilization (IVF) rate in rats.

Materials And Methods: In this experimental study, left varicocele were induced as the test group (n=18) which was further sub-divided into three groups based on the study termination time (4, 6 and 8 months after varicocele induction).