Effectiveness of N-acetylcysteine for preserving residual renal function in patients undergoing maintenance hemodialysis: multicenter randomized clinical trial.

Background: To investigate the efficacy and safety of oral N-acetylcysteine (NAC) for preserving residual renal function in patients undergoing hemodialysis.

Methods: Randomized, multi-center, parallel-group, open-label clinical trial (Registration No. IRCT 2014071418482N1).