First in-human clinical performance of a new non-cavitating handheld lensectomy system in 665 consecutive cataract surgeries.

Purpose: To investigate the intraoperative performance and lens fragmentation efficacy of a non-cavitating handheld lensectomy system in mild, moderate, and severe cataract.

Setting: Ambulatory surgical centers.

Design: Retrospective consecutive case series.

Microinterventional endocapsular nucleus disassembly: novel technique and results of first-in-human randomised controlled study.

Aim: To assess the safety and efficacy of microinterventional endocapsular nuclear fragmentation in moderate to severe cataracts.

Methods: This was a prospective single-masked multisurgeon interventional randomised controlled trial (ClinicalTrials.gov NCT02843594) where 101 eyes of 101 subjects with grade 3‒4+ nuclear cataracts were randomised to torsional phacoemulsification alone (controls) or torsional phacoemulsification with adjunctive endocapsular nuclear fragmentation using a manual microinterventional nitinol filament loop device (miLOOP group).

Explanted multifocal intraocular lenses.

Unlabelled: We report 2 cases in which single-piece multifocal acrylic intraocular lenses (IOLs) were explanted because of complications related to the presence of glistenings in the bulk of the IOL optic. In both cases, the patients complained about blurry or hazy vision. In vivo slitlamp examinations prior to IOL explantation confirmed the presence of severe glistenings in the IOL optic in 1 case and moderate glistenings in the second case.

Hydrogel sealant versus sutures to prevent fluid egress after cataract surgery.

Purpose: To evaluate the effectiveness of a hydrogel sealant versus a suture in preventing fluid egress after wound leakage in cataract surgery.

Setting: Twenty-four ophthalmic clinical practices in the United States.

Design: Prospective randomized parallel-arm controlled multicenter subject-masked study.