Reinfection and reactivation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have recently raised public health pressing concerns in the fight against the current pandemic globally. In this study, we propose a new dynamic model to study the transmission of the coronavirus disease 2019 (COVID-19) pandemic. The model incorporates possible relapse, reinfection and environmental contribution to assess the combined effects on the overall transmission dynamics of SARS-CoV-2.
View Article and Find Full Text PDFComput Math Methods Med
September 2018
This paper aims to study the dynamics of immune suppressors/checkpoints, immune system, and BCG in the treatment of superficial bladder cancer. Programmed cell death protein-1 (PD-1), cytotoxic T-lymphocyte-associated antigen 4 (CTLA4), and transforming growth factor-beta (TGF-) are some of the examples of immune suppressors/checkpoints. They are responsible for deactivating the immune system and enhancing immunological tolerance.
View Article and Find Full Text PDFIn this paper, we formulated a mathematical model that studies the dynamics of HIV/AIDS in Turkey from 1985 to 2016. We find two equilibrium points, disease free equilibrium and endemic equilibrium. Global stability analysis of the equilibria was conducted using Lyapunov function which depends on the basic reproduction ratio .
View Article and Find Full Text PDFIn this paper, we developed a mathematical model to describethe dynamics of Aflatoxins in plants, animals, and humans. Fourequilibrium points were found, and their stability analyses wereconducted using threshold quantities. If both are less than one, thestandardized toxic limit is not exceeded, while if both are greater thanone it is exceeded in both animals and humans.
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