Publications by authors named "Farnoosh Fathali-Zadeh"
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Synopsis of recent research by authors named "Farnoosh Fathali-Zadeh"
- Farnoosh Fathali-Zadeh's research primarily focuses on the molecular and clinical implications of genetic variants in the context of hereditary breast cancer, particularly examining the BRCA2 gene.
- In a 2012 study, Fathali-Zadeh characterized a variant of uncertain significance (VUS) in the BRCA2 gene by analyzing the co-expression of this variant with wild-type mRNA in multiple families affected by breast cancer.
- The research includes a comprehensive approach utilizing DNA sequencing, case-control studies, evolutionary data analysis, and in-silico predictions to explore the clinical significance of the identified VUS, contributing valuable insights into the genetics of breast cancer susceptibility.
