Publications by authors named "Farnaz Valizadeh"
Reactive oxygen species-inducing itraconazole and its anti-biofilm activity against resistant Candida parapsilosis sensu lato biofilm cells isolated from patients with recalcitrant onychomycosis.
Monireh Kamali Aliasghar Ghaderi Pegah Tamimi Alireza Firooz Mansour Nasiri Kashani Farnaz Valizadeh
Arch Dermatol Res
September 2024
Article Synopsis
- Candida parapsilosis is a major fungus contributing to nail infections, known for forming biofilms that resist standard antifungal treatments.
- This research focused on evaluating the effectiveness of the antifungal drug itraconazole against biofilms of C. parapsilosis, examining its ability to induce reactive oxygen species (ROS) that lead to cell death.
- The findings suggest that targeting ROS can enhance the effectiveness of antifungal therapy, particularly for stubborn cases of nail fungus, highlighting the potential of itraconazole as a key treatment option.
Background And Purpose: This review aimed to compare the efficacy of acidifying agents and clotrimazole in the treatment of patients with otomycosis.
Materials And Methods: The databases, including Research Gate, Google Scholar, ScienceDirect, Embase, Medline, Scopus, Cochrane, and library databases of clinical trials were searched in this study. The keywords were "Fungal Ear Infection" and "Otitis External" for otomycosis, "Clotrimazole", Lotrimin", "Mycelex", "Desenex", and "Clotrimaderm Mycoderm" for clotrimazole, and "Boric Acid Alcohol", "Alcohol-vinegar solution", Burow solution (Domeboro), "Isopropyl Alcohol", "VoSol" and "Acetic Acid" for acidifying agents.