Publications by authors named "Farnaz Sepandar"

Pemphigus vulgaris (PV) is a chronic autoimmune disorder with potentially fatal outcomes. The aim of this study was to investigate the effect of l-carnitine (LC) on secreted frizzled-related protein-5 (SFRP5), omentin, visfatin, and glycemic indices in PV patients under corticosteroid treatment. In this randomized, double-blind, placebo-controlled clinical trial, 52 patients with PV were divided randomly into two groups to receive 2 g of LC or a placebo for 8 weeks.

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Pemphigus vulgaris (PV) is a severe, bullous, autoimmune disease of the skin and mucous membranes. Corticosteroids are usually the main core treatment for controlling PV, which could lead to several side effects such as insulin resistance, osteoporosis, and cardiovascular disorders. The aim of this study is to evaluate the protective effects of l-carnitine (LC) supplementation in PV patients under corticosteroid treatment.

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Aims: Adipokines play a major role in developing metabolic syndrome (MetS), and it has been found that there is a significant relationship between MetS and resting metabolic rate (RMR) in obese people. The present study aimed to investigate the mediatory effect of adipokines on the RMR-MetS relationship.

Methods: This cross-sectional study included 263 obese and overweight women, mean BMI 33.

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