Publications by authors named "Farmakis H"
Background: We verified the possibility of using laser Doppler fluxmetry for prolonged monitoring of hepatic perfusion; we confirm the ability of an implantable laser Doppler microprobe to be in constant 'optical contact' with the liver and thus to transmit a stable microcirculatory signal for a prolonged period of time, and we correlate the response of liver microcirculation to the hepatic artery blood flow reduction in order to estimate this flow by continuous monitoring of microcirculation.
Method: Hepatic microcirculation was recorded by a single-fiber microprobe implanted in the livers of 8 dogs and of 5 surgical ICU patients. In another 7 dogs, liver microcirculation as well as hepatic artery blood flow were recorded digitally, while an occluder was used to decrease hepatic artery flow.
Background: Experimental studies have shown that elevation of intraabdominal pressure by means of gas insufflation produces hemodynamic disturbances in the peritoneal viscera, leading to splanchnic ischemia. The purpose of this clinical investigation is to reproduce the experimental data in humans undergoing laparoscopic cholecystectomy.
Methods: Sixteen females participated in this study.