Publications by authors named "Farina Arreguin-Gonzalez"
Background: Langerhans cell histiocytosis (LCH) is a rare neoplastic disease characterized by clonal proliferation of den-dritic cells. It is Mexico's ninth most frequent malignancy in patients under 18 years of age. The aim of the study was to determine the clinical characteristics, treatment, and survival of Mexican pediatric patients diagnosed with LCH treated from January 2010 to December 2018.
View Article and Find Full Text PDFBackground: The evaluation of existing resources and services is key to identify gaps and prioritize interventions to expand care capacity for children with central nervous system (CNS) tumors. We sought to evaluate the resources for pediatric neuro-oncology (PNO) in Mexico.
Methods: A cross-sectional online survey with 35 questions was designed to assess PNO resources and services, covering aspects including number of patients, infrastructure, human resources, and diagnostic and treatment time intervals.
Introduction: Data on medulloblastoma outcomes and experiences in low- and middle-income countries, especially in Latin America, is limited. This study examines challenges in Mexico's healthcare system, focusing on assessing outcomes for children with medulloblastoma in a tertiary care setting.
Methods: A retrospective analysis was conducted, involving 284 patients treated at 21 pediatric oncology centers in Mexico.
Background: Anthracycline-induced cardiotoxicity is a frequent complication that can occur at any stage of treatment, even in survivors.
Objective: To determine maximum aerobic power, quality of life, and left ventricular ejection fraction in childhood cancer survivors treated with anthracyclines.
Design: Cross-sectional, observational study.
Article Synopsis
- Brainstem tumors make up 10.9% of all brain tumors, with pediatric diffuse intrinsic pontine gliomas (DIPG) having a poor prognosis; this study focuses on children in Mexico from 2001 to 2021, analyzing clinical characteristics and prognostic factors for survival.
- A total of 110 patients were included, with a median diagnosis age of 7 years; symptoms appeared within 6 months for over half the patients, and despite treatment, the overall survival rate at 4 years was only 11.4%.
- The study emphasizes the need for improved healthcare strategies in Mexico and highlights challenges regarding the acceptance of palliative care among families and medical staff.
Objetivo: Describir los efectos cardiovasculares del tratamiento del cáncer infantil en supervivientes mediante métodos clínicos, electrocardiográficos y ecocardiográficos. Material y métodos: Estudio transversal y observacional de casos y controles de 34 pacientes de una clínica de supervivientes de cáncer infantil, evaluados de forma clínica, con electrocardiograma, ecocardiografía convencional y strain. Edad promedio de 13.
View Article and Find Full Text PDFObjective: Mature B-cell non-Hodgkin lymphoma (B-NHL) comprises more than 50% of all non-Hodgkin lymphoma (NHL) in children and adolescents. An official report published by the Mexican National Center for the Control and Prevention of Cancer in the Pediatric and Adolescent Populations, reported a lymphoma OS of 71% (including all Hodgkin and NHL). The Mexican Association of Pediatric Oncology and Hematology conducted a retrospective study to analyze the clinical characteristics and outcomes of children with diagnosis of B-NHL in Mexico, in order to perceive the main areas of improvement in the health care.
View Article and Find Full Text PDFArticle Synopsis
- * The term "lineage switch" refers to acute leukemias that initially show one type (lymphoid or myeloid) but change to the opposite type upon relapse.
- * A case is reported involving a 4-year-old with acute myeloid leukemia who, upon relapse, switched to acute lymphoblastic leukemia, indicating the emergence of a new leukemic clone based on various characteristics.