Publications by authors named "Fariha Tanveer"
The COVID-19 pandemic has not only burdened healthcare systems but has also led to a new emerging medical enigma that is post-COVID-19 syndrome or "long COVID." Characterized by persistent symptoms that extend beyond the acute phase of the illness, long COVID has rapidly become a public health concern with ambiguous neurological and neuropsychiatric dimensions. This narrative review aims at synthesizing available research to decode the long-term impacts of COVID-19 on neurological and mental health.
View Article and Find Full Text PDFEpidermal growth factor receptor (EGFR) is the most frequently overexpressed receptor histologically exhibited by oral squamous cell carcinoma (OSCC) patients. Aberrated EGFR signaling may lead to recurrence and metastasis, thus laying the foundation of targeted therapy. Deactivating EGFR is likely to prevent downstream signaling thus resulting in apoptosis.
View Article and Find Full Text PDFArticle Synopsis
- Overexpression of EGFR in cancers like oral squamous cell carcinoma makes it a target for therapy, with quinazoline-based TKIs being explored as potential treatments.
- The study used GOLD and AutoDock Vina docking programs to evaluate the binding of four anti-EGFR drugs to the EGFR structure, revealing that varlitinib was prioritized by GOLD while imatinib was favored by AutoDock Vina.
- Ultimately, varlitinib was concluded to be the most effective EGFR inhibitor due to its high fitness score and stable interactions identified through the in silico analysis.