Publications by authors named "Faridun Rahimi"

Article Synopsis
  • Modified balloons (MB) and rotational atherectomy (RA) are used to treat coronary plaques with calcium, but data on their safety during hospital stays is limited.
  • A study analyzed over 32,000 patients in Germany from 2017 to 2020 comparing the outcomes of RA and MB, finding that RA patients were generally older and had more serious heart conditions.
  • It was concluded that while both procedures had similar risks for major adverse events, RA was associated with higher rates of complications like bleeding and pericardial puncture, although patients at high-volume centers had shorter hospital stays and fewer acute cerebrovascular events.
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Background: Evidence on the optimal timing of RA is scarce, although increased periprocedural complications for unplanned procedures have been reported.

Aims: To compare planned versus unplanned use of rotational atherectomy (RA) for plaque modification in patients with severely calcified coronary lesions.

Methods: Procedural and 1-year follow-up data of planned (n = 562 lesions in 448 vessels of 416 patients) and unplanned (n = 490 lesions in 435 vessels of 403 patients) RA between 2008 and 2020 were analyzed using the propensity score methods.

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Background: The prognostic impact of contrast-associated acute kidney injury (CA-AKI) in patients undergoing chronic total occlusion (CTO) percutaneous coronary intervention (PCI) remains underestimated.

Methods: We examined 2707 consecutive procedures performed in a referral CTO center between 2015 and 2019. CA-AKI was defined as an increase in serum creatinine ≥ 0.

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Background: A significant proportion of patients presenting with acute myocardial infarction (MI) has no coronary obstruction at coronary angiography and no other obvious non-coronary pathophysiology causing MI. These patients are classified as MI with non-obstructive coronary arteries (MINOCA). Data on incidence and predictors of MINOCA are still limited.

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Objective: This study sought to evaluate the diagnostic performance of the 1-hour troponin algorithm for diagnosis of myocardial infarction (MI) without persistent ST-segment elevations (non-ST-segment MI (NSTEMI)) in a cohort with a high prevalence of MI. This algorithm recommend by current guidelines was previously developed in cohorts with a prevalence of MI of less than 20%.

Design: Prospective cohort study from November 2015 until December 2016.

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Rationale: Platelets are known to play a crucial role in hemostasis. Sphingosine kinases (Sphk) 1 and 2 catalyze the conversion of sphingosine to the bioactive metabolite sphingosine 1-phosphate (S1P). Although platelets are able to secrete S1P on activation, little is known about a potential intrinsic effect of S1P on platelet function.

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