Publications by authors named "Farid Yousefi"
Background: The emergence of a new pandemic SARS-CoV-2 (COVID-19) resulted in a high mortality rate across the world. This study sought to comprehensively analyze the Case Fatality Rate (CFR) associated with COVID-19 in the Khuzestan province of Iran". The primary objective was to discern patterns and determinants influencing CFR, shedding light on the evolving impact of the pandemic on morbidity and mortality.
View Article and Find Full Text PDFAs an antibody-based therapy, plasma therapy has been used as an emergency therapeutic strategy against severe acute respiratory syndrome coronavirus type 2 infection. Due to the critical role of macrophages in coronavirus disease-19 (COVID-19)-associated hyperinflammation, the main objective of this study was to assess the effect of plasma transfusion on the expression levels of the inflammatory biomarkers involved in activation and pulmonary infiltration of macrophages. The target population included 50 severe hospitalized COVID-19 patients who were randomly assigned into 2 groups, including intervention and control.
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- Global real-time monitoring of SARS-CoV-2 variants is essential for controlling COVID-19, leading to the development of a Sanger-based platform for variant tracking in low-resource labs.
- The study utilized nested RT-PCR and Sanger sequencing on 1,028 samples, achieving high concordance with whole genome sequencing for mutation detection and lineage assignment.
- The new method is effective for tracking variants of concern like Delta and Alpha, making it a viable option for countries with limited resources to monitor SARS-CoV-2 variants efficiently.
Article Synopsis
- The study analyzed the genetic diversity of SARS-CoV-2 in Iran over one year, following two independent viral introductions during the early outbreak phase.
- Researchers sequenced 319 whole genomes between March 2020 and May 2021 to monitor the circulating viral lineages.
- Results showed that different SARS-CoV-2 clades dominated various waves of infection, with the Delta variant emerging as a crucial factor in the fifth wave, highlighting significant mutations in key lineages.
Background: The coronavirus disease 2019 (COVID-19) has become the leading source of pneumonia outbreaks in the world. The present study aimed to compare the condition of intensive care unit (ICU) and non-ICU COVID-19 patients in terms of epidemiological and clinical features, laboratory findings, and outcomes in three cities across Iran.
Methods: In a cross-sectional study, 195 COVID-19 patients admitted to five hospitals across Iran during March-April 2020 were recruited.
Background: From the beginning of the COVID-19 pandemic, the development of infrastructures to record, collect and report COVID-19 data has become a fundamental necessity in the world. The disease registry system can help build an infrastructure to collect data systematically. The study aimed to design a minimum data set for the COVID-19 registry system.
View Article and Find Full Text PDFEvaluating the effect of convalescent plasma (CP) on some cytokine storm indices in severe COVID-19 patients. Totally, 62 patients were randomly assigned into two groups for this clinical trial. Patients in the intervention group received one unit (500 mL) plasma on the admission day plus standard drugs while the controls merely received standard treatments.
View Article and Find Full Text PDFThe SARS-CoV-2 virus has been rapidly spreading globally since December 2019, triggering a pandemic, soon after its emergence. While Iran was among the first countries confronted with rapid spread of virus in February 2020, no real-time SARS-CoV-2 whole-genome tracking in early phase of outbreak was performed in the country. To address this issue, we provided 50 whole-genome sequences of viral isolates ascertained from different geographical locations in Iran during March-July 2020.
View Article and Find Full Text PDFPrevalence of SARS-CoV-2 in Patients with Severe Pneumonia in Khuzestan Province, Iran.
Iran J Allergy Asthma Immunol
October 2020
Article Synopsis
- * Out of 909 samples, 36.08% tested positive for SARS-CoV-2 via real-time PCR, with slightly more cases showing lung abnormalities (ground-glass opacity) on CT scans.
- * The research highlights that while CT scans detected more lung issues, real-time PCR remains the primary method for diagnosing SARS-CoV-2 infections in patients.
The present study surveyed demographic and infection data which were obtained after open heart surgery (OHS) through patient's admission in Golestan teaching hospital, Ahvaz metropolitan city of Iran, taking into account the confirmed location of the infection, microorganism and antibiotic susceptibility. The occurrence of infection among patients during 48 to 72 h after surgery and hospital admission is the definition of Nosocomial infections (NIs) (Salmanzadeh et al., 2015) [1].
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- Hepatitis B virus (HBV) significantly contributes to chronic liver diseases, making vaccination crucial for prevention, especially among medical personnel exposed to high-risk situations.
- A study conducted in a teaching hospital in Ahvaz, Iran, aimed to evaluate the post-vaccination immune status of medical staff and identify factors influencing non-response rates to the HBV vaccine.
- Of the 239 medical staff assessed, 6% were non-responders, with age over 50 and conditions like diabetes and use of immunosuppressive drugs linked to a higher likelihood of non-response.
Introduction: Pseudomonas luteola is an uncommon opportunistic pathogen. It is recognized as an uncommon cause of infections in underlying medical disorders. Infections caused by this microorganism are health care associated.
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