Publications by authors named "Farid Shokry Ataya"

The widespread utilization of synthetic chemicals contaminates the land and water environments. The present investigation determined the effects of sub-lethal concentrations of lufenuron in the male Japanese quail. The birds exposed to lufenuron showed the clinical signs of behavioral, digestive, nervous and reproductive upsets.

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Pesticides, including fipronil, are used mainly in agriculture; however, in veterinary and animal husbandry, their potential use is to control the pests responsible for vector-borne diseases. Their residues in agriculture products and direct use on farms are responsible for potentially harming livestock and poultry. So, this study was designed to evaluate the toxico-pathological effects of fipronil on the immune system of poultry birds.

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Pymetrozine (a pyridine azomethine pesticide) is one of the most commonly and frequently used insecticides. Scanty information is available about the deleterious effects of Pymetrozine on fish especially bighead carp. Hence, the current study investigated chronic toxicological effects of pymetrozine in bighead carp.

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Olive Leaves Extract (OLE) holds therapeutic potential, traditionally used to treat hepatic ailments, though its molecular mechanisms remain unclear. This study evaluated the efficacy of ethanolic OLE against Carbon Tetrachloride (CCl)-induced oxidative stress in a rat model. Phytochemical analysis was performed using High Performance Liquid Chromatography (HPLC).

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The biological properties of herbs and essential oils (EOs), such as their antibacterial, analgesic, anti-inflammatory, antioxidant, and anticancer characteristics, make them widely used in a variety of fields. This research aims to assess the antibacterial efficacy of lavender oil against Staphylococcus aureus (S. aureus) and Pseudomonas aeruginosa (P.

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The comparative analysis of homologous enzymes is a valuable approach for elucidating enzymes' structure-function relationships. Glutathione transferases (GSTs, EC. 2.

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The research aims to elucidate how drug interactions affect the activity of L-asparaginase (L-ASNase), an essential enzyme in cancer treatment, especially for acute lymphoblastic leukemia (ALL). Understanding these interactions is crucial for optimizing treatment effectiveness and reducing adverse effects. This study explores the intricate molecular interactions and structural dynamics of L-ASNase upon binding with colchicine.

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For a sustainable ecology, slaughterhouse sludge must be managed effectively in preview of the parasitic or coliforms' spill over to the community. In order to determine the effectiveness of a customized biological decomposer solution in lowering the parasitic eggs and coliform bacteria, three composting units (Unit 1, Unit 2, and Unit 3) were treated with its different amounts. Over a period of 60 days, pH, temperature, humidity, number of the parasitic eggs per gram (EPG) of faecal material, viability of eggs, and coliform counts were evaluated.

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  • A study in Narowal, Punjab, found that 72.92% of ruminants slaughtered were infected with gastrointestinal parasites, with goats having the highest infection rate at 78.63%.
  • Female ruminants experienced significantly higher infection rates (85.62%) than males (65.13%).
  • The research revealed a severe economic impact, estimating annual losses of approximately Pak. Rs. 405.09 million (around USD 1.43 million) due to organ condemnation from GI parasites.
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  • * Quail given higher doses of acetochlor (20mg/kg, 30mg/kg, and 40mg/kg) showed reduced growth, changes in crowing behavior, and significant alterations in blood parameters, including decreases in red blood cells and hemoglobin levels.
  • * Histopathological examinations revealed serious lesions in key organs such as testes, heart, and brain, illustrating that even low acetochlor concentrations can adversely affect the physical and biochemical health of Japanese quail.
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L-asparaginase is a remarkable antineoplastic enzyme used in medicine for the treatment of acute lymphoblastic leukemia (ALL) as well as in food industries. In this work, the L-asparaginase-II gene from Salmonella paratyphi was codon-optimized, cloned, and expressed in E. coli as a His-tag fusion protein.

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  • Yaks are crucial food animals in China but are commonly affected by bacterial diarrheal diseases with limited treatment options.
  • This study tested the effectiveness of a probiotic and berberine treatment on yak calves, revealing that treated calves showed better weight gain and lower diarrhea scores compared to those infected without treatment.
  • The research also highlighted changes in gut microbiota, showing that the treatment improved the overall gut health of yaks by increasing beneficial bacteria and reducing harmful ones, suggesting potential new therapies for ruminant diarrhea.
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  • Magnesium oxide nanoparticles (MgO NPs) are increasingly used in biomedicine and agriculture but pose environmental risks, particularly concerning water ecosystems.
  • A study was conducted on grass carp to assess the toxic effects of MgO NPs, with fish exposed to varying concentrations (0.5 mg/L and 0.7 mg/L) over 21 days, while a control group remained unexposed.
  • Results indicated that higher doses of MgO NPs caused significant oxidative stress, DNA damage, and reduced antioxidant enzyme levels in the fish, highlighting adverse impacts on their physiological functions even at low concentrations.
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Hepatic diseases pose a significant threat to community health, impacting the quality of life and longevity of millions worldwide. Despite revolutionary advancements in treatment, liver diseases remain a pressing issue, necessitating the development of more effective therapeutic approaches. Here, we conducted a comprehensive multi-omics analysis to investigate the underlying mechanism of Swertiamarin in alleviating hepatic injuries induced by CCl in mice.

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  • The Baihe River, located in Northern Sichuan, is rich in natural resources but the effects of livestock on its water microbiome haven't been studied.
  • Water samples from areas with yaks and sheep were collected and analyzed, revealing significantly lower diversity and functionality in microbial communities compared to the river's water.
  • The presence of harmful microorganisms and antibiotic-resistant bacteria was much higher near livestock areas, indicating that livestock activities negatively impact water quality and microbial health.
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The widespread application of herbicides raises concerns about their impact on non-target aquatic organisms. This study aimed to evaluate the toxicity of a commercially available herbicide formulation containing Bromoxynil+MCPA (2-Methyl-4-chlorophenoxyacetic acid) on Cirrhinus mrigala (economically significant fish). A total of 210 juvenile fish were subjected to a triplicate experimental setup, with 70 fish allocated to each replicate, exposed to seven different concentrations of herbicide: 0 mg/L, 0.

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Diarrhea is a severe issue in calves that causes fertility problems and economic issues worldwide. Sodium acetate/sodium butyrate (SA/SB) alleviates diarrhea in mice; however, little information is available about the preventive effect of SA/SB on diarrheic yak calves living on the Tibet plateau. Yak calves (n = 19) of age ≥4 months and weight 37 ± 2 Kg were randomly divided into control (C, n = 10) and supplement groups (S, n = 9).

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  • - Drug addiction leads to severe health risks, including cardiovascular issues, cancer, and mental health disorders, with illicit drugs like cannabinoids and opioids being a major concern for their harmful effects on health.
  • - The study analyzed toxic elements (arsenic, cadmium, mercury, and nickel) in drug-abusing patients' biological samples and found significantly higher concentrations of these elements compared to a control group, indicating serious health implications.
  • - Results suggest that elevated toxic elements could contribute to infections and other health issues among drug users, highlighting the need for further research to understand long-term effects and treatment options as well as the socio-economic impacts of substance abuse.
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The hyperactivity of urease enzymes plays a crucial role in the development of hepatic coma, hepatic encephalopathy, urolithiasis, gastric and peptic ulcers. Additionally, these enzymes adversely impact the soil's nitrogen efficiency for crop production. In the current study 100 known drugs were tested against Jack Bean urease and urease and identified three inhibitors i.

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Duck adenovirus type-3 (DAdV-3) is a poorly characterized duck virus. A comprehensive analysis of the DAdV-3 pathogenicity and host immune response could be a valuable addition. Herein, DAdV-3 was isolated from Muscovy duck and virus-specific genes were confirmed by polymerase chain reaction (PCR).

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  • The hyperactivity of the urease enzyme can lead to health issues like gastritis and peptic ulcers; natural and synthetic inhibitors can help reduce these problems.
  • A specific group of compounds called triazolothiadiazoles and triazolothiadiazines have shown potential as antiurease agents, with several compounds demonstrating strong inhibitory effects.
  • Studies indicate these compounds work through competitive inhibition and interact with important sites in the urease enzyme, suggesting they could be developed into effective medications.
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  • The study investigates postpartum uterine infections in cattle, focusing on the prevalence of pathogenic bacteria, their resistance profiles, and the effectiveness of sodium alginate-based antibiotics and nanoparticles.
  • Findings showed significant resistance in bacteria against common antibiotics, with a notable 60% resistance to fusidic acid and other drugs among different bacteria strains.
  • Gel-based formulations demonstrated lower minimum inhibitory concentrations, indicating promising antibacterial properties, while MgO nanoparticles appeared safe for broader applications and suggested the need for further research into effective and affordable treatments.
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Diarrhea in calves is a common disease that results in poor nutrient absorption, poor growth and early death which leads to productivity and economic losses. Therefore, it is important to explore the methods to reduce diarrhea in yak's calves. Efficacy of lactic acid bacteria (LAB) for improvement of bacterial diarrhea is well recognized.

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