Basophil Activation Test With Aspergillus Molecules: The Case for ABPA.

Background: Allergic bronchopulmonary aspergillosis (ABPA) is an underestimated allergic disease due to (AF). The main diagnostic criteria for ABPA rely on the evaluation of immunoglobulin (Ig) E and IgG responses to AF extracts, although these cannot discriminate AF-sensitization from ABPA.

Objectives: To evaluate the performance of cellular functional assays with extract and molecular AF allergens in ABPA.

Skin necrosis following local anesthetic: Same presentation for two different diagnoses.

Background: Local anesthetics (LA) are widely used in medicine and are generally well tolerated. Although most adverse reactions are nonallergic, LA are a frequent reason for allergy consultation.

Objective: We want to expand the differential diagnosis of adverse reactions to LA by presenting rare diagnoses.