Effect of bioactive ceramic and recombinant human transforming growth factor-beta (rhTGF-beta) on regeneration of parietal bone defects in rat.

Aims: The purpose of this study was to evaluate the regenerative response of parietal bone defects in rats to bioactive ceramic and TGF-beta 1.

Materials And Methods: Sixty mature adult rats with initial weights of 300 g to 324 g were used. The diameter of each defect was 3 mm.