Publications by authors named "Fariborz Mansourghanaei"
Background: Papillary thyroid carcinoma (PTC) is the predominant form of thyroid cancer, and the presence of extrathyroidal extension (ETE) significantly impacts treatment decisions and prognosis. Accurate preoperative detection of ETE remains challenging, highlighting the need to evaluate advanced imaging techniques.This systematic review and meta-analysis aimed to investigate the diagnostic accuracy of magnetic resonance imaging (MRI) in detecting extrathyroidal extension (ETE) among patients diagnosed with papillary thyroid carcinoma (PTC).
View Article and Find Full Text PDFBackground: Diabetes mellitus (DM) is highly consequential to global health among chronic diseases. Due to a limited researches that have examined relationships between liver enzymes and DM, this study aimed to investigate the link between elevated liver enzymes and diabetes among Prospective Epidemiological Research Studies in Iran (PERSIAN) Guilan cohort study (PGCS) population.
Methods: This cross-sectional study was conducted on 10519 individuals.
Background: This study investigated the association between hypertension and oral health status, as measured by the Decayed, Missing, and Filled Teeth (DMFT) index, using data from the PERSIAN Guilan Cohort Study (PGCS).
Methods: A cross-sectional analysis was conducted on 10,520 participants aged 35-70 from Guilan Province, Northern Iran. Blood pressure measurements, oral examinations, and comprehensive data collection on demographic, lifestyle, and clinical factors were performed.
Introduction: There is a relationship between excess body weight and the risk of a number of infectious diseases, including urinary tract infections (UTIs). This study aimed to investigate the correlation between body mass index (BMI) and UTIs among Prospective Epidemiological Research Studies of the Iranian Adults (PERSIAN) Guilan Cohort Study (PGCS) population.
Methods: This cross-sectional study was conducted on 10,520 individuals aged 35-70 years from PGCS.
Article Synopsis
- * Researchers found that the average age girls start their periods is about 14 years, but it has been getting younger over the past 100 years.
- * Different countries showed different trends, with some like China having ups and downs, while others like Japan and Singapore had a steady decline in the average age.
Background: Primary aldosteronism (PA) is now recognized as the most prevalent form of secondary hypertension globally, contributing significantly to cardiovascular morbidity and mortality. This umbrella review aims to systematically compare cardiovascular outcomes and all-cause mortality in PA patients undergoing adrenalectomy versus mineralocorticoid receptor antagonist (MRA) treatment, aiming to inform optimal management strategies.
Method: Following PRISMA guidelines (Supplemental Digital Content 1, http://links.
Background: Waist circumference (WC), or waist-to-hip ratio (WHR), potentially offers a more accurate reflection of intra-abdominal fat accumulation and could serve as a superior predictor of type 2 diabetes mellitus (T2DM) risk compared to BMI. The current study investigated the relationship between WHR and its influencing factors among diabetes patients enrolled in the Prospective Epidemiological Research Studies in Iran (PERSIAN) Guilan Cohort study (PGCS).
Method: In this cross-sectional study of 10,520 participants, 2,531 had T2DM.
Background: This study assessed the prevalence of gastroesophageal reflux disease (GERD) in a general adult population in Iran. The association between GERD and various factors was also evaluated.
Methods: We performed a cross-sectional study on 163,018 individuals aged over 35 who were enrolled in the PERSIAN cohort.
Article Synopsis
- A nationwide study in Iran investigated age and sex differences in outcomes among patients with Inflammatory Bowel Disease (IBD), utilizing data from the Iranian Registry of Crohn's and Colitis (IRCC).
- The analysis covered 9,392 adult IBD patients and revealed that male Crohn's disease (CD) patients had higher odds of active disease compared to females, while the opposite was true for ulcerative colitis (UC) patients.
- The study highlights the significance of incorporating age and sex differences into IBD understanding, which may help improve management strategies and promote personalized care for affected individuals.
Objective: The purpose of this study is to evaluate the association between elevated serum liver enzymes and Metabolic Syndrome (MetS) in Prospective Epidemiological Research Studies of the Iranian Adults (PERSIAN) Guilan Cohort Study (PGCS) population.
Methods: This cross-sectional study involved 10,519 individuals between the ages of 35 and 70 enrolled in the PGCS. The gathered data encompassed demographic information, anthropometric measurements, blood pressure, and biochemical indicators.
Background: Colorectal cancer (CRC) stands as the third most prevalent cancer globally, projecting 3.2 million new cases and 1.6 million deaths by 2040.
View Article and Find Full Text PDFThe Persian Eye Cohort Study, a population-based cross-sectional study from 2015 to 2020, examined refractive error prevalence among 48,618 Iranian adults aged 31 to 70. The study encompassed six centers in Iran, employing random cluster sampling for demographic, medical, and socioeconomic data collection through interviews. Ophthalmic exams included visual acuity, automated and manual objective refraction, subjective refraction, slit lamp, and fundus examinations.
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- Type 2 diabetes is a key factor contributing to non-alcoholic fatty liver disease (NAFLD), leading to increased fasting blood sugar, insulin levels, and insulin resistance in affected patients.
- This meta-umbrella study analyzed existing research on how gut microbial treatments (probiotics, prebiotics, and synbiotics) influence glycemic indices in NAFLD patients.
- Results indicated that these treatments significantly lowered insulin resistance and fasting insulin levels, but had no notable impact on fasting blood sugar levels.
The rapid emergence of multiple strains of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has sparked profound concerns regarding the ongoing evolution of the virus and its potential impact on global health. Classified by the World Health Organization (WHO) as variants of concern (VOC), these strains exhibit heightened transmissibility and pathogenicity, posing significant challenges to existing vaccine strategies. Despite widespread vaccination efforts, the continual evolution of SARS-CoV-2 variants presents a formidable obstacle to achieving herd immunity.
View Article and Find Full Text PDFCan modulation of gut microbiota affect anthropometric indices in patients with non-alcoholic fatty liver disease? An umbrella meta-analysis of randomized controlled trials.
Ann Med Surg (Lond)
May 2024
Background And Aim: Modulating the gut microbiota population by administration of probiotics, prebiotics, and synbiotics has shown to have a variety of health benefits in different populations, particularly those with metabolic disorders. Although the promising effects of these compounds have been observed in the management of patients with non-alcoholic fatty liver disease (NAFLD), the exact effects and the mechanisms of action are yet to be understood. In the present study, we aimed to evaluate how gut microbiota modulation affects anthropometric indices of NAFLD patients to achieve a comprehensive summary of current evidence-based knowledge.
View Article and Find Full Text PDFBackground: Data on the epidemiology of inflammatory bowel disease (IBD) in the Middle East are scarce. We aimed to describe the clinical phenotype, disease course, and medication usage of IBD cases from Iran in the Middle East.
Methods: We conducted a cross-sectional study of registered IBD patients in the Iranian Registry of Crohn's and Colitis (IRCC) from 2017 until 2022.
Background: This study aimed to investigate the frequency of colorectal lesions in the first-degree relatives of patients with colorectal lesions among the Prospective Epidemiological Research Studies in Iran (PERSIAN )Guilan Cohort Study (PGCS) population.
Methods: In this cross-sectional study, 162 first-degree relatives with a history of colorectal lesions were randomly selected from 52 participants in PGCS. All subjects underwent total colonoscopy by a gastroenterologist, and a pathologist evaluated colorectal biopsies.
Although hematuria is not life-threatening, some could be the result of a more severe condition. Our objectives are to report on the prevalence and risk factors of asymptomatic microscopic hematuria (AMH) in the prospective epidemiological research studies of the Iranian adults (PERSIAN) Guilan cohort study (PGCS) population. This cross-sectional study was conducted from 2014 to 2017 and consisted of 10,520 individuals aged 35-70.
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- A retrospective study compared the clinical features and treatment of early-onset (children/adolescents) and elderly-onset inflammatory bowel disease (IBD) patients to understand differences in disease manifestation and progression.
- The study found that early-onset IBD patients commonly had a more aggressive disease phenotype and used more intensive treatments like prednisolone and anti-TNF medications compared to elderly patients.
- Notably, elderly-onset ulcerative colitis patients exhibited less aggressive disease and were less likely to require the same level of medication as their early-onset counterparts.
Article Synopsis
- Alzheimer's disease is influenced by many factors like genetics, age, and infections, making it a complicated illness.
- Scientists are paying more attention to how tiny organisms, like bacteria and viruses, in our body can affect brain health and possibly lead to Alzheimer's.
- New research shows that special molecules called non-coding RNAs might help control how these diseases develop, which could lead to new ways to treat or prevent Alzheimer's.
Article Synopsis
- The study examined ultrasound-measured gallbladder volume among 957 adults to understand its relationship with demographic factors.
- The results indicated that factors such as gender, body mass index (BMI), metabolic equivalent of task (MET), and cardiovascular disease (CVD) significantly impacted gallbladder volume.
- Despite finding associations with these factors, there was no significant link between gallbladder lesions and overall volume.
Article Synopsis
- - The meta-analysis examined the impact of a positive family history of cancer on colorectal cancer (CRC) risk in EMRO countries, analyzing 27 relevant articles from databases like PubMed and Scopus.
- - The research utilized the Newcastle-Ottawa checklist to ensure article quality and calculated odds ratios (OR) to compare cases with controls, revealing a significant association between family history and CRC risk (OR 2.21; P < 0.001).
- - The findings emphasize the need for timely screening and early detection for at-risk individuals, suggesting that improved coordination in healthcare facilities and increased screening could lower CRC mortality rates and financial costs for the public.
Article Synopsis
- This study looked at how walking exercises can help people prepare for a colonoscopy, which is a test doctors do to look inside the intestines.
- It involved 262 patients who were split into two groups: one group did walking exercises and the other group didn't, but both followed similar eating and medicine plans.
- Results showed that the group that walked more had better bowel preparation, even though there wasn't a big difference in the average scores overall between the two groups.
Background: Botox injections are commonly used for cosmetic and therapeutic purposes because they temporarily paralyze muscles, reduce wrinkles, and alleviate certain medical conditions. Although generally considered safe and effective, Botox injections may cause potential complications. While herpes reactivation is more commonly associated with immunosuppressive therapies, such as chemotherapy or corticosteroid use, its association with Botox injection is poorly documented.
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