Publications by authors named "Fariborz Khorvash"
Article Synopsis
- - The study reviews the neuroprotective effects of fasting on neurodegenerative disorders and identifies mechanisms like changes in brain structure/function and gut microbiota modulation.
- - Preclinical research in animal models reveals that fasting influences metabolic pathways, improves cell survival in CNS tumors, and interacts with circadian rhythms and immune responses through gut microbiome changes.
- - While fasting shows potential as a non-drug treatment for neurodegenerative conditions, more research is needed to support these initial findings and develop effective clinical practices.
Background: Migraine is one of the most debilitating neurological disorders that causes frequent attacks of headaches and affects approximately 11% of the global population. Deficient or even insufficient levels of vital nutrients would increase the severity and frequency of migraine attacks. Therefore, we aimed to examine the practical supplements for the prevention and management of migraine attacks.
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- Migraine is a significant public health issue, and not all routine treatments work for everyone, often leading to side effects.
- This study examined the combined effects of vitamin D and probiotics on migraine symptoms, daily functioning, mental health, and inflammation markers in a controlled trial involving patients aged 18 to 55.
- Results showed that the co-supplementation significantly improved serum vitamin D levels and reduced both the frequency and severity of migraines compared to a placebo, highlighting potential alternative treatment options for migraine sufferers.
Article Synopsis
- Migraine is a common and debilitating neurological disorder, with potential contributing factors including inflammation, oxidative stress, and nutrient deficiencies; nutrition-based approaches might provide safer and more affordable symptom management.
- This study will randomly assign 80 women aged 20 to 50 to receive a co-supplement of alpha-linolenic acid and L-carnitine, or placebos, over 12 weeks, aiming to measure the effectiveness through migraine symptoms and various health markers.
- The research aims to explore whether the combination of these nutrients can improve migraine symptoms, as well as impact mental health, sleep quality, and overall quality of life for patients.
Background: Opium use disorder is a significant health problem in our country, leading to a considerable number of health issues. Opium has several detrimental effects on its consumers. However, the effect of Opium use disorder on intracerebral hemorrhage (ICH) has not been evaluated.
View Article and Find Full Text PDFMigraine is a complex neurovascular disorder characterized by recurrent headache attacks that are often accompanied by symptoms such as vomiting, nausea, and sensitivity to sound or light. Preventing migraine attacks is highly important. Recent research has indicated that alterations in gut microbiota may influence the underlying mechanisms of migraines.
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- The article presents the first national guidelines for managing acute coronary syndrome (ACS) in Iran, detailing diagnosis, treatment, and secondary prevention strategies.
- A group of specialists examined clinical concerns and formulated 13 key questions, leading to recommendations based on systematic evidence review.
- The guidelines include initial response protocols for chest pain, risk categorization for patients, treatment options in hospitals, and strategies for secondary prevention post-ACS.
Objective: Increased body mass index (BMI) seems to be a risk factor for migraine attacks. Cinnamon has anti-inflammatory, neuroprotective, and anti-obesity effects. This study aimed to assess the effects of cinnamon on anthropometric indices and headache-related disability of patients with migraine.
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- This guideline is Iran's first systematic approach for diagnosing and managing hyperlipidemia in adults, addressing key clinical questions with evidence-based recommendations.
- It sets specific thresholds for LDL-C (over 190 mg/dL) and triglycerides (over 500 mg/dL) to initiate drug treatment while emphasizing lifestyle changes as the primary intervention.
- Statins are recommended as the first-line medication, with additional options proposed for high levels, and targets for LDL-C (<130 mg/dL) and triglycerides (<200 mg/dL) are specified for adults without comorbidities.
Background And Aim: The present double-blinded randomized clinical trial aimed to investigate the effect of selenium supplementation on oxidative stress, clinical, and physiological symptoms in patients with migraine.
Methods: In total, 72 patients with migraine were randomly assigned to receive either 200 μg/day selenium ( = 36) or placebo ( = 36) for 12 weeks. Clinical traits of migraine (e.
The Efficacy of Repetitive Transcranial Magnetic Stimulation (rTMS) versus Transcranial Direct-Current Stimulation (tDCS) on Migraine Headaches: A Randomized Clinical Trial.
Adv Biomed Res
January 2024
Background: Non-pharmacologic prophylactic methods for chronic migraine have been developed, including the promising non-invasive techniques of repetitive transcranial magnetic stimulation (rTMS) and transcranial direct-current stimulation (tDCS). This study aimed to compare the efficacy of rTMS and tDCS on pain intensity, the impact of headaches on daily life, anxiety, and depression in migraine headaches patients.
Materials And Methods: This randomized clinical trial was conducted on 72 patients with migraine headaches, randomly allocated to the rTMS and tDCS groups.
We investigated the relationship between dietary phytochemical index (DPI) and migraine headaches in Iranian patients, analyzing both clinical and psychological traits. A cross-sectional study was conducted using non-obese adults aged 20-50 years who were diagnosed with migraine. The study used a validated 168-item food frequency questionnaire to assess the usual dietary intake of participants.
View Article and Find Full Text PDFBackground: Despite a number of recommended strategies, effective treatment of migraine remains elusive. Given the role of oxidative stress in the pathogenesis of migraine, selenium, as an antioxidant nutrient, may have a beneficial effect on migraine outcomes. However, no study has explored the effects of selenium supplementation on migraine symptoms, oxidative stress biomarkers, and mental health.
View Article and Find Full Text PDFAims: In this study, we aimed to evaluate the relationship between the dietary inflammatory index (DII) and mental health outcomes among patients with migraine headaches.
Methods: In this cross-sectional study, 262 subjects were included. The dietary intakes were collected using a validated 168-item semi-quantitative food frequency questionnaire.
Aims: There is a paucity of evidence regarding the benefit of royal jelly (RJ) on post-stroke complications in patients with ischemic stroke. To address this knowledge gap, this randomized, triple-blind, placebo-controlled clinical trial was carried out to determine the effects of RJ consumption on post-stroke clinical outcomes.
Methods: Of 64 eligible ischemic stroke patients (45-80 years), 32 were randomized to the RJ and 32 to the placebo groups and completed a 12-week intervention.
Background: Stroke is a leading cause of death worldwide, which is associated with a heavy economic and social burden. The purpose of this study was to investigate the effects of supplementation with curcumin-piperine combination in patients with ischemic stroke in the rehabilitation stage.
Methods: In this randomized controlled trial, 66 patients with stroke were randomized into two groups receiving curcumin-piperine tablets (500 mg curcumin + 5 mg piperine) and matched placebo tablets for 12 weeks.
Cerebrovascular diseases comprise a significant portion of neurological disorders related to coronavirus disease 2019 (COVID-19). We evaluated the clinical and imaging characteristics of a cohort of COVID-19 patients with stroke and also identified patients with watershed infarcts. In this cross-sectional study, seventy-three COVID-19 patients with ischemic stroke were included between October 2020 and January 2021.
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- Migraine is a chronic condition primarily affecting women, which can lead to disabling headaches and associated symptoms; the study explores the role of gut health in migraine management.
- Researchers are conducting a randomized, double-blind trial with 80 women to assess the effects of 10 g of inulin supplementation daily over 12 weeks, compared to a placebo.
- The trial aims to measure various outcomes, including headache frequency, inflammatory markers, and quality of life, potentially offering new insights into treating migraines through gut microbiota modulation.
Background: Foods rich in flavonoids are associated with a reduced risk of various chronic diseases, including Alzheimer's disease (AD). In fact, growing evidence suggests that consuming flavonoid- rich foods can beneficially affect normal cognitive function. Animal models have shown that many flavonoids prevent the development of AD-like pathology and improve cognitive deficits.
View Article and Find Full Text PDFAims: There is limited evidence on the link between diet quality and migraine headaches. The present study aimed to evaluate the association between dietary diversity score (DDS), as a good representative of overall diet quality, and clinical features of migraine headaches.
Methods: In total, 262 subjects (224 females and 34 males), aged 20 to 50 years old were included in the present cross-sectional study.
Aims: We evaluated associations between diet quality and migraine outcomes.
Methods: The current work represented a cross-sectional study on 262 patients with migraine (20-50 y). Diet quality was assessed using the standard healthy eating index 2015 (HEI-2015) and alternative healthy eating index 2010 (AHEI-2010).
Background: We aimed to investigate the usefulness of intracranial arterial pulsatility index to assess the prognosis of lacunar infarcts.
Materials And Methods: Forty-nine patients with confirmed acute lacunar infarct were enrolled in the study. A transcranial color-coded sonography was performed to assess the pulsatility index of bilateral middle cerebral, posterior cerebral, vertebral, and proximal internal carotid arteries.
Background: Stroke is a debilitating disease that affects over 15 million people worldwide each year, resulting in the death of one-third of those people and severe disability in two-thirds of survivors. Previous studies reported various health benefits of Royal jelly in the context of its anti-inflammatory properties. We will aim to investigate the effects of royal jelly supplementation on oxidative stress, inflammatory mediators, mental health, cognitive function, quality of life, and clinical outcomes of patients with ischemic stroke.
View Article and Find Full Text PDFBackground: Structural planning is essential for the management of constipation in stroke patients. The current study aims to determine the impact of a care plan on the frequency of new-onset constipation following stroke. Materials and Methods.
View Article and Find Full Text PDFObjective: Migraine is one of the most common diseases. Curcumin with anti-oxidative and anti-neuroinflammatory properties might have beneficial effects in migraine patients. This study will be conducted to evaluate the effects of a phytosomal preparation of curcumin on clinical signs, oxidative stress, and inflammatory parameters in patients with migraine.
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