Study of carD gene sequence in clinical isolates of Mycobacterium tuberculosis.

Mycobacterium tuberculosis growth rate is closely coupled to rRNA transcription which is regulated through carD gene. The aim of this study was to determine the sequence of carD gene in drug susceptible and resistant clinical isolates of M. tuberculosis and designing of a PCR assay based on carD sequence for rapid detection of this bacterium.

Prevalence of QTc interval changes in acute psychiatric care: a cross-sectional study.

Introduction: In a case series we examined the prevalence and incidence of QT changes during a 1-week interval in hospitalized patients in a general psychiatry ward during a 6-month period.

Method: This cross-sectional study was done on electrocardiographic QT interval of patients admitted to the Psychiatric Department of Taleghani Hospital during a 6-month period excluding subjects with underlying cause of QT prolongation.

Results: Admission and follow-up electrocardiograms of 27 men and 47 women were studied, there was significant QT prolongation during hospitalization (P value 0.

Sudden cardiac death after treatment with low dose risperidone in combination with cotrimoxazole.

Unlabelled: Risperidone as an antipsychotic drug raises the risk of serious ventricular tachyarrhythmias and sudden cardiac death; co-administered with other potentially arrhythmogenic drugs the risk escalates. There are some electrocardiographic markers which may help predict such events.

Case Report: We describe a 47-year-old woman with acute psychosis, who died suddenly subsequent to refractory ventricular arrhythmia, while on low dose risperidone combined with cotrimoxazole.