Synthesis of 1,2,4-triazole-based deep eutectic solvents modified nickel ferrite nanoparticles and their application in dispersive solid phase extraction of triazole pesticides prior to LC-MS/MS analysis.

A dispersive solid phase extraction method using new magnetic nanoparticles based on nickel ferrite was introduced for the extraction of six triazole pesticides (penconazole, hexaconazole, tebuconazole, diniconazole, triadimefon, and difenoconazole) from water samples before liquid chromatography-tandem mass spectrometry analyses. Initially, a new deep eutectic solvent was synthesized with 1,2,4-triazole and n-octanol for surface modification of the nanoparticles easily achieved through microwave radiation. The nanoparticles morphology, magnetic properties, adsorption capacity, isotherms, and crystalline patterns of the sorbent were examined.

Development of a deep eutectic solvent-based ultrasound-assisted homogenous liquid-liquid microextraction method for simultaneous extraction of daclatasvir and sofosbuvir from urine samples.

An ultrasound-assisted homogenous liquid-liquid microextraction method using a new deep eutectic solvent was proposed for the extraction of daclatasvir and sofosbuvir from urine. The analytes were determined by high performance liquid chromatography-diode array detector. The deep eutectic solvent was prepared by mixing p-aminophenol with tetrabutyl ammonium chloride.

Development of a stir bar sorptive extraction method coupled to solidification of floating droplets dispersive liquid-liquid microextraction based on deep eutectic solvents for the extraction of acidic pesticides from tomato samples.

A stir bar sorptive extraction method coupled with deep eutectic solvent based solidification of floating organic droplets-dispersive liquid-liquid microextraction has been used for the simultaneous derivatization and extraction of some acidic pesticides in tomato samples. In this method, initially the analytes are adsorbed on a coated stir bar from tomato juice filled in a narrow tube. After extraction, the stir bar is removed and a water-miscible deep eutectic solvent is used to elute the analytes.