Characterization and optimization of magnetic molecularly imprinted nanofibers for determination of sunitinib in human serum and capsule samples.

This article reports a spectrofluorometric method for the determination of sunitinib (STB) drug based on molecularly imprinted nanofibers fabricated by the electrospinning method and modified by magnetic nanoparticles as sorbent. The characterization of magnetic molecularly imprinted nanofibers (MMINs) was carried out using X-ray diffraction (XRD), scanning electron microscope (SEM), and transmission electron microscopy (TEM), which confirmed the successful synthesis of MMINs with well-distributed magnetite nanoparticles. Drug adsorption and desorption were optimized and important parameters such as sample pH, nanofiber mass, adsorption and desorption time, eluent solvent and sample volume were analyzed.

High performance electrochemical method for simultaneous determination dopamine, serotonin, and tryptophan by ZrO-CuO co-doped CeO modified carbon paste electrode.

In this research, a paste containing ZrO-CuO-CeO ternary nanocomposite and graphene (Gr) was used in constructing a carbon paste sensor for monitoring biomolecules including dopamine (Dop), serotonin (Ser) and tryptophan (Trp). The scanning electron microscope (SEM), energy-dispersive X-ray spectroscopy (EDS), and X-ray diffraction (XRD) were utilized for ZrO-CuO-CeO ternary nanocomposite characterization. The obtained data show that, the ZrO2-CuO-CeO/Gr and synergetic effect of using these three-metal oxide nanoparticles, could effectively improve the electron transfer kinetic and exhibit a high electrocatalytic activity, making it serve as a powerful tool for biomolecules analysis.

Determination of ᴅ-phenylglycine in the presence of its ʟ-enantiomer using a turn-on fluorescent nano-chemosensor.

This paper reports on application of ʟ-tryptophan modified magnetite nanospheres (TryMNSs) as a novel fluorescent chiral selector for selective and sensitive determination of ᴅ-phenylglycine (ᴅ-Phy) in the presence of its enantiomer (i.e. ʟ-phenylglycine, ʟ-Phy).