Publications by authors named "Fariba Akrami"
Article Synopsis
- Pathogenic strains of Escherichia coli, known as avian pathogenic E. coli (APEC), pose significant health risks to both poultry and the public, prompting a systematic review of their characteristics from 189 research papers.
- The review found that serogroup O78 was the most prevalent (16%), with notable sequence types (ST117, ST140) linked to human pathogenic E. coli infections and identified diverse phylogenetic groups within poultry.
- Antimicrobial resistance was prevalent among APEC strains against several antibiotics, and virulence factors related to adherence and cytotoxicity were common, underscoring the need for better monitoring and control measures in poultry management.
Multidrug-resistant (MDR) Escherichia coli strains have rapidly increased worldwide, and effective antibiotic therapeutic options are becoming more restricted. As a polymyxin antibiotic, colistin has a long history of usage, and it is used as a final line of treatment for severe infections by Gram-negative bacteria (GNB) with high-level resistance. However, its application has been challenged by the emergence of E.
View Article and Find Full Text PDFRelationships between Efflux Pumps and Emergence of Heteroresistance: A Comprehensive Study on the Current Findings.
Can J Infect Dis Med Microbiol
September 2022
Heteroresiatnce (HR) is the type of resistance toward one or more antibiotics appearing as a population of the bacterial load consisting of one or more subpopulations with lower antibiotic susceptibility levels than others. Due to the lack of appropriate diagnosis of HR isolates and their importance in resistance emergence to antibiotics, investigating the origins, emergence factors, and HR inhibitors is critical in combating antibiotic resistance. Efflux pumps (EPs) are bacterial systems that own an influential role in acquiring resistance toward anti-bacterial compounds.
View Article and Find Full Text PDFIntegrons are a segment of dsDNA that play a major role in bacterial adaptation and evolution. These genetic determinants are known by the presence of three necessary apparatuses: an integrase ( gene), (a promoter) and (a recombination site). These elements are able to acquire gene cassettes, which can carry antibiotic resistance factors, by site-specific recombination mechanism.
View Article and Find Full Text PDFMulti-drug resistant isolates of Acinetobacter baumannii have created therapeutic problems worldwide. This current study was intended to determine the Integron types, gene cassettes and antimicrobial resistance profile of A. baumannii isolated from BAL samples in Babol, north of Iran.
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