The possible protective role of HLA B27 and relevant immune markers in Juvenile Idiopathic Arthritis patients.

Background & Objectives: JIA is a disease with different immunological characteristics and a complicated genetic foundation. HLA B27 is a risk factor for the development of JIA, and its impact on immunopathogenesis of the disease is also an area of interest. To determine whether HLA B27 and immune markers varied between JIA patients and healthy population.

Lipid profiles of non-diabetic healthy and ischaemic heart disease patients.

Objective: To find any difference in the fasting lipid profile in patients with history of ischaemic heart disease (IHD) and established atherosclerotic plaques on angiography and in subjects with no known history of IHD.

Study Design: Observational, cross-sectional study.

Place And Duration Of Study: Immunology Department of University of Health Sciences, Lahore, from January 2007 to January 2009.

Association of interleukin-4 and IgE levels with LDL oxidation in atherosclerosis.

Background: Atherosclerosis is an inflammatory and multifactorial disease, with a high prevalence rate in Pakistan.

Objective: To find a relation between serum IL-4 and IgE levels with oxidized LDL in atherosclerosis.

Methods: In this observational, cross sectional study 99 male patients, between forty and sixty years of age, with a history of ischemic heart disease (IHD) and established atherosclerotic plaques on angiography were recruited.

Relationship of white blood cell counts, haemoglobin and ESR with IHD.

Objectives: To find any association of white blood cells, haemoglobin and ESR with ischemic heart disease in high risk native population.

Methodology: The study included 93 male patients with Ischemic heart disease, between 40 and 60 years of age; 96 age and gender matched subjects. All study participants were non-diabetics.