Protective efficacy of extract on spermatogenesis in streptozotocin-induced diabetic rats.

Men with diabetes frequently experience spermatogenic dysfunction, which is the most significant sign that diabetes has harmed their ability to reproduce. The effect of various doses of the hydro-alcoholic extract of leaves on the pituitary-gonadal axis, sperm motility and number, antioxidant system, changes in testicular tissue structure, and spermatogenesis in healthy and diabetic rats has been examined in the current study. Eighty male rats that had been streptozotocin-induced diabetic and healthy were divided into eight groups: (1) control, (2) (50 mg/kg), (3) (100 mg/kg), (4) (200 mg/kg), (5) DM (6) DM+ (50 mg/kg), (7) DM+ (100 mg/kg) and (8) DM+ (200 mg/kg) and were administered orally for 48 days consecutive.