Dual Fluorimetric Sensor for Tandem Detection of Cadmium and Cysteine: An Approach for Designing a Molecular Keypad Lock System.

A fluorimetric sensor for dual and sensitive detection of Cd ion and Cysteine (based on 2-picolylamine platform) was developed.The sensor was designed and synthesized by simple condensation method and characterized by using common spectroscopic methods. The observations made from the kinetics of absorption and emission profile shows that probe Pdac behaves as ''ON-OFF'' fluorescent quenching sensor for cadmium ions.

A quinoline-based fluorescent probe for selective detection and real-time monitoring of copper ions - a differential colorimetric approach.

A quinoline moiety was used as a building block for designing a probe for the selective detection of copper ions in a partially aqueous medium. We have developed a molecular sensing system which gives insight into the complex physiological and redox aspects of labile copper. The probe provides a colorimetric approach for distinguishing cuprous and cupric ions along with their simultaneous discrimination from other metal ions in the visible range of the spectrum.

Interaction mode of polycarbazole-titanium dioxide nanocomposite with DNA: Molecular docking simulation and in-vitro antimicrobial study.

A polycarbazole-titanium dioxide (PCz/TiO2-8) nanocomposite was synthesized for the first time by in-situ oxidative polymerization with APS as an oxidizing agent in the presence of TiO2 nanoparticles which was characterized by SEM, TEM, FT-IR, DTA and TGA techniques. The SEM and TEM results showed that PCz has polymerized on the surface of the TiO2. The results confirmed the incorporation of TiO2 in PCz indicating the formation of nanocomposite due to strong interaction between TiO2 and PCz matrix affecting the properties as compared to pristine PCz.

Synthesis, spectroscopic characterization, DNA interaction and antibacterial study of metal complexes of tetraazamacrocyclic Schiff base.

The template condensation reaction between benzil and 3,4-diaminotoulene resulted mononuclear 12-membered tetraimine macrocyclic complexes of the type, [MLCl(2)] [M=Co(II), Ni(II), Cu(II) and Zn(II)]. The synthesized complexes have been characterized on the basis of the results of elemental analysis, molar conductance, magnetic susceptibility measurements and spectroscopic studies viz. FT-IR, (1)H and (13)C NMR, FAB mass, UV-vis and EPR.

Template synthesis and physico-chemical characterization of 14-membered tetraimine macrocyclic complexes, [MLX(2)] [M=Co(II), Ni(II), Cu(II) and Zn(II)]. DNA binding study on [CoLCl(2)] complex.

The template condensation reaction between glyoxal and 1,8-diaminonaphthalene resulted a few novel mononuclear 14-membered tetraimine macrocyclic complexes of the type, [MLX(2)] [M=Co(II), Ni(II), Cu(II) and Zn(II), for X=Cl or NO(3)]. The stoichiometry and the nature of the complexes have been deduced from the results of elemental analyses and conductance data. The formation of macrocyclic framework has been inferred from the appearance of imine upsilon(CN) and upsilon(MN) band in IR spectra and the resonance signals observed in (1)H and (13)C-NMR spectra.

Synthesis and spectroscopic studies on complexes of N,N'-bis-(2-pyridinecarboxaldimine)-1,8-diaminonaphthalene (L); DNA binding studies on Cu(II) complex.

The Schiff base ligand, N,N'-bis-(2-pyridinecarboxaldimine)-1,8-diaminonaphthalene (L), obtained by the condensation of 2-pyridinecarboxaldehyde and 1,8-diaminonaphthalene, has been used to synthesize the mononuclear complexes of the type [MLCl(2)] [M=Co(II), Ni(II), Cu(II) and Zn(II)]. The newly synthesized ligand (L) and its complexes have been characterized on the basis of results of elemental analysis, molar conductance, magnetic susceptibility measurements, Job's method and spectroscopic studies viz., FT-IR, Mass, (1)H and (13)C NMR.