Publications by authors named "Fares Fares"
Seizures in a Child Post Renal Transplant: A Case of Disequilibrium Syndrome.
Saudi J Kidney Dis Transpl
February 2022
Article Synopsis
- Disequilibrium syndrome is a condition that often leads to neurological symptoms occurring suddenly after hemodialysis, caused by a sharp decrease in serum osmolality.
- The text presents a case involving a child who experienced disequilibrium syndrome after a kidney transplant, highlighting a unique aspect of the condition beyond typical dialysis cases.
- The case is compared to previously documented instances of disequilibrium syndrome to provide additional insights into its presentation and implications.
Synthesis of enones, pyrazolines and pyrrolines with gem-difluoroalkyl side chains.
Beilstein J Org Chem
November 2013
Starting from easily accessible gem-difluoropropargylic derivatives, a DBU-mediated isomerisation affords enones in fair yields with a gem-difluoroalkyl chain. These derivatives were used to prepare pyrazolines and pyrrolines with the desired gem-difluoroalkyl side chain by cyclocondensations in good yields and with excellent stereoselectivity. A one-pot process was also successfully developed for these sequential reactions.
View Article and Find Full Text PDFWe report the synthesis and characterization of a variety of trans-3,4-substituted cyclopentanones and the corresponding tosylhydrazone derivatives starting with diethyl fumarate. Protection of the keto group followed by selective monohydrolysis of esters was achieved, resulting in cyclopentanones with different substituents at positions 3 and 4. The tosylhydrazone derivative of each cyclopentanone intermediate was prepared in moderate to good yields.
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