Publications by authors named "Farah Mohamed Muse"

In patients with acute ischemic stroke, hemorrhagic transformation is a major complication after intravenous thrombolysis. This study aimed to investigate the relationship between serum magnesium levels and hemorrhagic transformation (HT) after thrombolytic therapy. We retrospectively analyzed data from 242 patients who received thrombolytic therapy at the Second Affiliated Hospital of the Wenzhou Medical University in China.

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Article Synopsis
  • * Seventy-four healthy participants were analyzed and categorized based on the severity of their WMH using the Fazekas scale, revealing that those with more severe WMH had significantly lower densities of retinal capillaries and thinner retinal nerve fiber layers.
  • * Findings suggest that impairments in retinal capillary structures are linked to brain health, indicating that OCT-A could help assess the impact of WMH on cognitive function and microvascular health.
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Acute ischemic stroke is a serious disease that endangers human health. In our efforts to develop an effective therapy, we previously showed that the potent, highly selective inhibitor of soluble epoxide hydrolase called 1-trifuoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea (TPPU) protects the brain against focal ischemia in rats. Here we explored the mechanism of TPPU action by assessing whether it could preserve blood-brain barrier integrity and reduce apoptosis in the brain during permanent middle cerebral artery occlusion in male Sprague-Dawley rats.

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