Copper nanoparticle and point defect formation in Cu-Na ion-exchanged glass using protons of 2 MeV energy.

There are several applications for irradiating materials with protons that could provide alternative methodologies to synthesize and induce the formation of new compounds of different size scales. In this study, we explored the effects of proton irradiation oncommercial glass silicate that was previously subjected to a Cu-Na ion exchange (IE) treatment at 600 °C for a duration of 60 min. The ion-exchanged glass samples were irradiated with protons (p) of 2 MeV energy at doses in the range of thousands of grays (3.

Vancomycin audit in the paediatric population: Patterns of use and appropriateness of therapeutic drug monitoring.

Aims: This study aims to investigate prescribing and therapeutic drug monitoring (TDM) practices for vancomycin in paediatrics at the Jordan University Hospital and to determine the impact of inaccuracies in TDM data on dosing decisions.

Methods: Patterns of vancomycin prescriptions, appropriateness of vancomycin dosing, duration, TDM, and the accuracy of the recorded dosing/sampling times were determined prospectively based on prespecified criteria. Finally, Monte Carlo simulations were undertaken using the mrgsolve-package in R to assess the effect of inaccuracies in recording dosing/sampling times on subsequent dose adjustments.