Publications by authors named "Fara Zela Mohd Radin"
Article Synopsis
- Beta thalassemia has a diverse range of mutations across different populations, necessitating accurate and cost-effective molecular characterization for screening and genetic counseling.
- Researchers developed six multiplex assays using MALDI-TOF mass spectrometry to detect 27 beta-thalassemia mutations in 165 patients, comparing its effectiveness with the Amplification Refractory Mutation System (ARMS).
- Results showed a high agreement rate (88.7%) between the two methods, with the MS method successfully identifying rare mutations missed by ARMS, confirming its potential as a superior and more efficient genotyping tool.
