Publications by authors named "Faqing Chen"
Article Synopsis
- The study examined drug resistance in HIV among newly diagnosed individuals in China from 2018 to 2023 to adapt treatment guidelines.
- Out of over 22,000 individuals, 4.36% had at least one transmitted drug resistance (TDR) mutation, with the most common being linked to nonnucleoside reverse transcriptase inhibitors.
- The prevalence of TDR mutations notably increased from 4.05% to 5.39% over the study years, supporting the ongoing use of NNRTI-based treatment regimens for HIV.
Article Synopsis
- China adopted the WHO's "treat all" policy in 2016, aiming to improve HIV care through the 95-95-95 targets, which include diagnosing 95% of HIV positive individuals, getting 95% of those diagnosed on treatment, and achieving viral suppression in 95% of treated individuals.
- Data from 2004 to 2023 showed significant advancements in these targets, correlating with a drop in new HIV infections, as evidenced by a dip in clustering frequency and a peak in cases documented in 2014.
- The study concludes that while progress has been made, China needs to focus on increasing efforts in the first "95" target to further reduce HIV transmission rates and improve overall outcomes.
Background: To investigate the prevalence rate of subjects at high risk for cardiovascular disease (CVD) and to analyze the influencing factors in different regions of Gansu Province.
Methods: We used data from the China Patient-centered Evaluative Assessment of Cardiac Events (PEACE) Million Persons Project (MPP), which screened 100,725 residents aged 35-75 years from 10 project sites in Gansu Province, China, from 2017 to 2022. In addition, a questionnaire survey, anthropometric measurements, and collection of biological samples were carried out.
Syntaxin 6 Enhances the Progression of Epithelial Ovarian Cancer by Promoting Cancer Cell Proliferation.
Asian Pac J Cancer Prev
June 2023
Objectives: The aim of this study is to evaluate the expression of syntaxin 6 (STX6) in epithelial ovarian cancer (EOC) and assess the effects of STX6 on the prognosis of patient.
Methods: Using information from the Kaplan-Meier Plotter database, the effects of STX6 expression on overall survival (OS) and progression-free survival (PFS) in ovarian cancer patients were examined. The clinical information of 147 patients with epithelial ovarian cancer was evaluated, and immunohistochemical staining was used to identify STX6 expression in postoperative tumor specimens, and the affection of STX6 expression on patient prognosis was assessed.
Background And Objectives: This study was undertaken to evaluate the status of iodine nutrition and thyroid function of women at different phases of gestation in an iodine sufficient rural area.
Methods And Study Design: 215 pregnant women in different trimesters were consecutively enrolled in iodine sufficient rural areas of Yongjing county of Gansu province, China. The blood samples and random urine samples were collected from them, and serum thyroid-stimulating hormone (TSH), free triiodothyronine (FT3), free thyroxin (FT4), thyroid peroxidase antibody (TPOAb), thyroglobulin antibody (TgAb) and urinary iodine were measured.