Publications by authors named "Faozia Pio"
The genetic landscape of urologic cancers has evolved with the identification of actionable mutations that impact diagnosis, prognosis, and therapeutic strategies. This narrative review consolidates existing literature on genetic mutations across key urologic cancers, including bladder, renal, prostate, upper tract urothelial, testicular, and penile. The review highlights mutations in DNA damage repair genes, such as BRCA1/2 and PTEN, as well as pathway alterations like FGFR and PD-L1 overexpression.
View Article and Find Full Text PDFThe Role of Whole-Gland and Focal Cryotherapy in Recurrent Prostate Cancer.
Cancers (Basel)
September 2024
Article Synopsis
- * Salvage prostatectomy is effective but can lead to significant complications and poor functional results, prompting interest in salvage cryotherapy as a safer alternative for localized recurrence.
- * This review focuses on the effectiveness of whole-gland and focal salvage cryotherapy, the importance of advanced imaging techniques like multiparametric MRI and PSMA-targeted PET, and how cryotherapy compares to other treatments like high-intensity focused ultrasound (HIFU).