Publications by authors named "Fanzhu Meng"

False smut caused by is one of the most destructive diseases in rice. The disease is primarily controlled with fungicides, leading to the development of fungicide resistance. Although spray-induced gene silencing (SIGS) has been utilized for disease management, it has not been applied to control rice false smut.

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Rice blast caused by is one of the most economically important rice diseases. Fungicides such as isoprothiolane (IPT) have been used extensively for rice blast control, but resistance to IPT in is an emerging threat. In this study, molecular mechanisms of resistance in IPT-resistant mutants were identified.

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Article Synopsis
  • Research on Garcinia oligantha Merr. revealed twelve new depsidone derivatives, named oliganthdepsidones A-L, identified through various spectroscopic techniques.
  • Oliganthdepsidone F demonstrated significant cytotoxic effects against multiple human cancer cell lines, with the strongest effects noted in HepG2 and A375 cells, showing IC values as low as 10.92 μM.
  • The compound was found to induce apoptosis, inhibit cell proliferation, and reduce migration and invasion in cancer cells, indicating potential as a therapeutic agent against certain cancers.
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Donkey milk is a traditional medicinal food with various biological activities. However, its production is very low, and lactating donkeys often experience oxidative stress, leading to a further decline in milk yield. In this study, we supplemented the diets of lactating donkeys with yeast selenium (SY) to investigate its effects on lactation performance, antioxidant status, and immune responses, and we expected to determine the optimum additive level of SY in the diet.

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Isoprothiolane (IPT) resistance has emerged in Magnaporthe oryzae, due to the long-term usage of IPT to control rice blast in China, yet the mechanisms of the resistance remain largely unknown. Through IPT adaptation on PDA medium, we obtained a variety of IPT-resistant mutants. Based on their EC50 values to IPT, the resistant mutants were mainly divided into three distinct categories, i.

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The point mutation R343W in MoIRR, a putative ZnCys transcription factor, introduces isoprothiolane (IPT) resistance in . However, the function of MoIRR has not been characterized. In this study, the function of MoIRR was investigated by subcellular localization observation, transcriptional autoactivation test, and transcriptomic analysis.

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Peach bacterial spot caused by pv. has become widespread in most peach-producing areas of China and has caused devastating losses to the peach industry. However, little is known about the population biology and epidemiology of pv.

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The present study deals with the synthesis of zeolite-loaded FeOOH@ZnO by hydrothermal method and investigates the effects of coexisting SO and PO ions in the aqueous solution on the adsorption performance for S. The results showed that the HNO-modified zeolite loaded with FeOOH@ZnO (FeOOH@ZnO/HZ) resulted in a maximum S removal rate of ≈98%. The adsorbent's performance on removing S was significantly enhanced, compared with NaOH and ZnCl-modified zeolites loaded with FeOOH@ZnO, and the adsorption was proved to be a heat-absorbing process.

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Article Synopsis
  • Peach bacterial spot, caused by a specific pathogen, is a major worldwide issue leading to significant economic losses, especially in China.
  • A new detection method using a combination of recombinase polymerase amplification (RPA) and CRISPR/Cas12a has been developed, allowing for rapid and accurate identification of the pathogen in peach samples.
  • This method is highly sensitive, easy to use, and delivers results within 2 hours, making it suitable for on-site diagnosis and monitoring in peach production areas.
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Isoprothiolane (IPT), a systemic fungicide, has been applied to control rice blast since the 1970s. Although resistance to IPT has been observed, the mechanism of resistance still has not been fully elucidated. In this study, nucleotide polymorphisms were detected between two IPT-resistant mutants generated in the lab, and their parental wild type isolates using a whole-genome sequencing approach.

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Key Points: It has been known for some time that sensory information of one type can bias the spatial perception of another modality. However, there is a lack of evidence of this occurring in individual neurons. In the present study, we found that the spatial receptive field of superior colliculus multisensory neurons could be dynamically shifted by a preceding stimulus in a different modality.

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To explore the role of NF-κB activation in the development of insulin resistance and investigate whether or not that the inhibition of NF-κB activation by PDTC will improve the insulin resistance of L6 cells exposed to HO. L6 cells were treated with HO, PDTC or both HO and PDTC for 4 hours. The uptake of glucose with stimulation of insulin, the expression of P38-MAPK, p- P38-MAPK, NF-κBp65, p- NF-κBp65, IRS-1, IRS-2, p-IRS-2, PI3K, IκBα, p- IκBα, caspase-8 and GLUT4, the production of ROS, TNF-α, IL-6 and IL-1β as well as the apoptosis rate of L6 cells were determined and compared in L6 treated with HO alone or both HO and PDTC.

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