Predicting high-quality ecologically suitable areas of Astragalus mongholicus Bunge based on secondary metabolites content using Biomod2 model.

Habitat requirements and species' ecological suitability are essential conditions for species conservation and management. Under the influence of different environmental variables, assessing the habitat quality of medicinal plants is an important issue to ensure the quality of medicinal plants and protect biodiversity. This study explores the impact of environmental variables on the distribution of Astragalus mongholicus Bunge (A.

Corporate driver management perspectives: A PLS-SEM-based analysis of the mechanism of bus crash injury severity factor effects.

In view of the suddenness, complexity and high-risk potential of bus crashes, the injury severity and its influencing factors have increasingly became the research focus in urban transportation safety management. The purpose of this study is to analyze the core elements of bus crash injury severity and its interaction mechanism, in order to provide a scientific basis for improving the bus operation safety. In this study, 283 crashes occurred in a Chongqing bus company from January to June 2022 were taken as samples around the dimensions of drivers' educational background, driving characteristics, weather, and corporate management strategies.

Investigating risk factors associated with injury severity in highway crashes: A hybrid approach integrating two-step cluster analysis and latent class ordered regression model with covariates.

Highway crashes are responsible for a significant number of severe and fatal injuries drawing considerable attention from transportation authorities and safety researchers. This paper aims to investigate the unobserved heterogeneous effects of various risk factors, such as pre-crash circumstances, environmental and road conditions, vehicle-involved information, and driver attributes on injury severities. Our methodology uses a hybrid approach that combines two-step cluster analysis and latent class ordered regression model with covariates.

Predicting the spatial distribution of three species under climate change using the MaxEnt model.

In the context of global warming, the habitats of , including , , and , have been substantially threatened and deteriorated in recent years. Little is known about the potential geographic dynamics of economically renowned species, including those used in sand fixation and traditional Chinese medicine, under climate change. Therefore, evaluating their potential habitat and determining the crucial environmental variables affecting , and under the driving force of global warming are extremely important.

Decolorization and detoxification of direct blue 5B by a Marinobacter-dominated halo-thermoalkalophilic consortium.

Azo dye-containing sewage is commonly detected at high salinity, temperature and pH. In this study, a halo-thermoalkalophilic azo dye decolorization consortium was enriched and named "consortium HL". Consortium HL which was dominated by Marinobacter (84.

Spatial distribution dynamics for Maxim. from 1970 to 2020.

At different time scales, a species will experience diverse distribution changes. For Maxim, the phenomenon is obvious, but the understanding of the spatial dynamics of under distinct time scales is poor. In this study, we modeled the potential distribution for for five time scales, 1970-1979, 1980-1989, 1990-1999, 2000-2009, and 2010-2019, with different occurrence data, and the Kuenm package was used to optimize the parameter combination.

Analysis of factors affecting crash under risk scenarios based on driver homogenous clustering.

Research on road safety has focused on analyzing the factors that affect crashes. However, previous studies have often neglected differences in crash causation among heterogeneous clusters of drivers. In particular, the differences in the combined effect mechanisms of the factors in the risk scenarios have not been completely explained.

Semantic Segmentation and Depth Estimation Based on Residual Attention Mechanism.

Semantic segmentation and depth estimation are crucial components in the field of autonomous driving for scene understanding. Jointly learning these tasks can lead to a better understanding of scenarios. However, using task-specific networks to extract global features from task-shared networks can be inadequate.

Predicting the comprehensive geospatial pattern of two ephedrine-type alkaloids for Ephedra sinica in Inner Mongolia.

Ephedra sinica Stapf. is a shrubby plant widely used in traditional Chinese medicine due to its high level of medicinal value, thus, it is in high demand. Ephedrine (E) and pseudoephedrine (PE) are key medicinal components and quality indicators for E.

Modeling for Predicting the Potential Geographical Distribution of Three Herbs in China.

species are beneficial for environmental protection in desert and grassland ecosystems. They have high ecological, medicinal, and economic value. To strengthen the protection of the sustainable development of , we used occurrence records of Stapf.

Priority planting area planning for cash crops under heavy metal pollution and climate change: A case study of Hort.

Introduction: Soil pollution by heavy metals and climate change pose substantial threats to the habitat suitability of cash crops. Discussing the suitability of cash crops in this context is necessary for the conservation and management of species. We developed a comprehensive evaluation system that is universally applicable to all plants stressed by heavy metal pollution.

Analyzing Commute Mode Choice Using the LCNL Model in the Post-COVID-19 Era: Evidence from China.

The purpose of this paper is to gain an insight into commuting and travel mode choices in the post-COVID-19 era. The surveys are divided into two waves in Qingdao, China: the first-wave questionnaires were collected under the background of a three-month zero growth of cases; the second wave was implemented after the new confirmed cases of COVID-19. The latent class nested logit (LCNL) model is applied to capture heterogeneous characteristics among the various classes.

[Planning of ecologically suitable areas for Ligusticum chuanxiong under background of soil cadmium pollution].

Chuanxiong Rhizoma is a traditional Chinese medicinal material mainly produced in Sichuan and Chongqing of China. In recent years, the cadmium content in Chuanxiong Rhizoma produced in most of the genuine producing areas has exceeded the standard, which makes Chuanxiong Rhizoma difficult to be exported. To solve the problem of excessive cadmium content in soil, this study employed the MaxEnt model to simulate the potential geographic distribution of Ligusticum chuanxiong and evaluate important environmental factors, and re-plan its ecologically suitable areas based on the mineral distribution characteristics and soil cadmium pollution status.

Glucopyranose from prevent alcoholic liver diseases by regulating Nrf2/HO-1-TLR4/NF-κB signalling pathways and gut microbiota.

This study investigated the effects of PGPs ( polysaccharides), a glucopyranose isolated from the mycelium of and characterized with the main chain of →4)-α-D-Glcp-(1→, on the prevention against alcohol liver diseases (ALD), with the aim of providing a theoretical basis for the application of as prebiotic agents in preventing and treating gut dysbiosis and alcohol-related metabolic disorders in individuals with ALD. The results showed that PGP treatment reduced oxidative stress by up-regulating the Nrf2/HO-1 signalling pathways, and decreased the pro-inflammatory factors by down-regulating TLR4/NF-κB signalling pathways. Furthermore, we validated effects of PGPs on balancing the gut-liver axis by maintaining the integrity of the intestinal epithelial barrier of decreasing intestinal permeability, increasing intestinal tight-junction protein and mucin expression and elevating the abundance of short-chain fatty acids (SCFAs) producers in the intestine by regulating the microbiota composition.

Predicting the suitable habitats of parasitic desert species based on a niche model with and as examples.

, an excellent tree species for sand fixation and afforestation in the desert areas of western China, is threatened by climate change and anthropogenic activities. The suitable habitat of this species is shrinking at a remarkable rate, although conservation measures have been implemented. is an entirely parasitic herb that occurs in deserts, is a source of "desert ginseng" worldwide, and has extremely high medicinal value.

Identification of Ligustici Rhizoma et Radix and its adulterants based on their chemical constituents by UHPLC-Q/TOF-MS combined with data mining.

Ligustici Rhizoma et Radix (LR), known as Gaoben (GB) in Chinese, has been used in traditional Chinese medicine for more than 2000 years. However, the varieties of LR are not well characterized at present, and traditional recognition methods have encountered increasing difficulties. This research attempts to distinguish different varieties of LR and its adulterants based on their chemical composition.

A new species of (Hypodematiaceae) from China.

J.X.Li, F.

Geographical classification of Epimedium based on HPLC fingerprint analysis combined with multi-ingredients quantitative analysis.

A reliable and comprehensive method for identifying the origin and assessing the quality of Epimedium has been developed. The method is based on analysis of HPLC fingerprints, combined with similarity analysis, hierarchical cluster analysis (HCA), principal component analysis (PCA) and multi-ingredient quantitative analysis. Nineteen batches of Epimedium, collected from different areas in the western regions of China, were used to establish the fingerprints and 18 peaks were selected for the analysis.

RNA interference targeting CYP76AH1 in hairy roots of Salvia miltiorrhiza reveals its key role in the biosynthetic pathway of tanshinones.

Plant cytochrome P450s (CYPs) are well known as the largest family of enzymes that contribute to both primary metabolism and the chemical diversity of plant secondary metabolites. It is important to elucidate the in vivo role of CYPs in secondary metabolism, in order to apply them in the production of valuable metabolites in medicinal plants via metabolic engineering. CYP76AH1 has been suggested to catalyze the conversion of the carbon skeleton miltiradiene into the intermediate ferruginol, which is involved in the biosynthesis of tanshinones, the chief bioactive ingredients of Salvia miltiorrhiza.

Deep Sequencing of the Scutellaria baicalensis Georgi Transcriptome Reveals Flavonoid Biosynthetic Profiling and Organ-Specific Gene Expression.

Scutellaria baicalensis Georgi has long been used in traditional medicine to treat various such widely varying diseases and has been listed in the Chinese Pharmacopeia, the Japanese Pharmacopeia, the Korean Pharmacopoeia and the European Pharmacopoeia. Flavonoids, especially wogonin, wogonoside, baicalin, and baicalein, are its main functional ingredients with various pharmacological activities. Although pharmaological studies for these flavonoid components have been well conducted, the molecular mechanism of their biosynthesis remains unclear in S.

Cellular and Subcellular Immunohistochemical Localization and Quantification of Cadmium Ions in Wheat (Triticum aestivum).

The distribution of metallic ions in plant tissues is associated with their toxicity and is important for understanding mechanisms of toxicity tolerance. A quantitative histochemical method can help advance knowledge of cellular and subcellular localization and distribution of heavy metals in plant tissues. An immunohistochemical (IHC) imaging method for cadmium ions (Cd2+) was developed for the first time for the wheat Triticum aestivum grown in Cd2+-fortified soils.

[Analysis on formula raw materials application of health food containing Gardeniae fructus].

In this article we built formula database of health food containing Gardeniae Fructus with Traditional Chinese Medicine Inheritance Support System (V2.0). And on this basis, use data mining method such as association rules of the software, to analyze commonly used formula raw materials or materials combination of formula containing Gardeniae Fructus and raw material application having assisted function formula to protect chemical liver injury.

Mucoadhesive microparticles for gastroretentive delivery: preparation, biodistribution and targeting evaluation.

The aim of this research was to prepare and characterize alginate-chitosan mucoadhesive microparticles containing puerarin. The microparticles were prepared by an emulsification-internal gelatin method using a combination of chitosan and Ca2+ as cationic components and alginate as anions. Surface morphology, particle size, drug loading, encapsulation efficiency and swelling ratio, in vitro drug released, in vitro evaluation of mucoadhesiveness and Fluorescence imaging of the gastrointestinal tract were determined.

Using a thermoluminescent dosimeter to evaluate the location reliability of the highest-skin dose area detected by treatment planning in radiotherapy for breast cancer.

Acute skin reaction during adjuvant radiotherapy for breast cancer is an inevitable process, and its severity is related to the skin dose. A high-skin dose area can be speculated based on the isodose distribution shown on a treatment planning. To determine whether treatment planning can reflect high-skin dose location, 80 patients were collected and their skin doses in different areas were measured using a thermoluminescent dosimeter to locate the highest-skin dose area in each patient.

Studies of the microbial metabolism of flavonoids extracted from the leaves of Diospyros kaki by intestinal bacteria.

Flavonoid glycosides are metabolized by intestinal bacteria, giving rise to a wide range of phenolic acids that may exert systemic effects in the body. The microbial metabolism of flavonoids extracted from the leaves of Diospyros kaki (FLDK) by intestinal bacteria was investigated in vitro. High-performance liquid chromatography/linear trap quadrupole orbitrap mass spectrometry was performed to analyze the metabolites of flavonoids in vivo using Xcalibur2.