The impact of terminating cost-sharing reductions payments on health insurance plan choices.

The Trump administration terminated cost-sharing reductions (CSRs) payments to health insurers in 2017, while still required insurers to provide CSRs to eligible enrollees in the Marketplace. Marketplace administration data reveals that, in response to this termination, insurers raised premiums to compensate for their loss. Consequently, premium increases led to more advanced premium tax credits for enrollees in the Marketplace.

Performance evaluation of plastic optical fiber communication using micro-lens coupling and computational temporal ghost imaging algorithm.

Plastic optical fiber communication (POFC) systems are particularly sensitive to signal performance and power budget. In this paper, we propose what we belive to be a novel scheme to jointly enhance the bit-error-ratio (BER) performance and coupling efficiency for multi-level pulse amplitude modulation (PAM-M) based POFC systems. The computational temporal ghost imaging (CTGI) algorithm is developed for PAM4 modulation for the first time to resist the system distortion.

Cutoff Point of Mini-Balance Evaluation Systems Test Scores for Elderly Estimated by Center of Pressure Measurements by Linear Regression and Decision Tree Classification.

Background: Understanding balance ability and assessing the risk of possible falls are very important for elderly rehabilitation. The Mini-Balanced Evaluation System Test (Mini-BESTest) is an important survey for older adults to evaluate subject balance, but it is not easy to complete due to various limitations of physical activities, including occasional fear of injury. A center of pressure (CoP) signal can be extracted from a force pressure plate with a short recording time, and it is relatively achievable to ask subjects to stand on a force pressure plate in a clinical environment.

Effects of soluble Antarctic krill protein-curcumin complex combined with photodynamic inactivation on the storage quality of shrimp.

A new protein complex (SAKP-Cur) was successfully prepared by combining soluble Antarctic krill protein with curcumin through hydrophobic action. The potency of photodynamic inactivation (PDI) mediated by the complex on preserving the storage quality of shrimp at 4 °C was investigated by microbiological, chemical, physical and histological methods. Results showed that the SAKP-Cur significantly improved the stability of curcumin, and greatly inactivated the native bacteria in shrimp driven by PDI.

Extraction of Interface-Trap Densities of the Stacked Bonding Structure in 3D Integration Using High-Frequency Capacitance-Voltage Technique.

An extraction method of the interface-trap densities () of the stacked bonding structure in 3D integration using high-frequency capacitance-voltage technique is proposed. First, an accurate high-frequency capacitance-voltage model is derived. Next, by numerically solving the charge-balance equation and charge conservation equation, is extracted by fitting the measured and calculated capacitance-voltage curves based on the derived model.

Aldo-Keto Reductase 1C3 Mediates Chemotherapy Resistance in Esophageal Adenocarcinoma via ROS Detoxification.

Esophageal adenocarcinoma (EAC) is one of the most lethal malignancies, and limits promising treatments. AKR1C3 represents a therapeutic target to combat the resistance in many cancers. However, the molecular mechanism of AKR1C3 in the chemotherapy resistance of EAC is still unclear.

Method for controlling temperature sensitivity of the fiber intermodal sensor and its application in the torsion sensor.

Temperature crosstalk has always been a critical problem for fiber intermodal sensors. In this work, we have proposed a novel method based on the special temperature response of photosensitive fiber to control the temperature sensitivity of the fiber intermodal sensor. The control of temperature sensitivity has been realized via adjusting the proportion of photosensitive fiber to single-mode fiber in the sensing part.

Targeting Glutaminolysis: New Perspectives to Understand Cancer Development and Novel Strategies for Potential Target Therapies.

Metabolism rewiring is an important hallmark of cancers. Being one of the most abundant free amino acids in the human blood, glutamine supports bioenergetics and biosynthesis, tumor growth, and the production of antioxidants through glutaminolysis in cancers. In glutamine dependent cancer cells, more than half of the tricarboxylic/critic acid (TCA) metabolites are derived from glutamine.

Linking Cancer Stem Cell Plasticity to Therapeutic Resistance-Mechanism and Novel Therapeutic Strategies in Esophageal Cancer.

Esophageal cancer (EC) is an aggressive form of cancer, including squamous cell carcinoma (ESCC) and adenocarcinoma (EAC) as two predominant histological subtypes. Accumulating evidence supports the existence of cancer stem cells (CSCs) able to initiate and maintain EAC or ESCC. In this review, we aim to collect the current evidence on CSCs in esophageal cancer, including the biomarkers/characterization strategies of CSCs, heterogeneity of CSCs, and the key signaling pathways (Wnt/β-catenin, Notch, Hedgehog, YAP, JAK/STAT3) in modulating CSCs during esophageal cancer progression.

[Investigation on rates of awareness, treatment and control of diabetes mellitus and the influence factors in rural areas of Jilin province].

Objective: Assess the rates of awareness, treatment and control of diabetes mellitus and the influence factors in rural areas of Jilin province.

Methods: Multistage stratified random cluster sampling design was used to select participants that carried out with questionnaire interview and physical examination. The analysis was based on a representative sample of 923 diabetes mellitus.

[Analysis of dyslipidemia among patients with diabetes mellitus in Jilin Province communities].

Objective: To investigate the pattern of dyslipidemia in patients with diabetes mellitus in Jilin province communities, and to provide a theoretical basis for the management of dyslipidemia among patients with diabetes.

Method: Based on the prevalence and risk factors of chronic diseases survey among adults in Jilin Province 2012 used multistage stratified random sampling design, a total of 1825 community residents aged 18 -79 years-old with diabetes mellitus in 9 districts of Jilin Province undergo the survey with questionnaire(age, gender, history of chronic disease in the past one year), blood index detection (blood glucose, total cholesterol high density lipoprotein cholesterol, low density lipoprotein cholesterol and triglycerides), and anthropometric (height and weight).

Result: Among 1825 patients with diabetes, 883 males (48.