Influence of antiresorptive/antiangiogenic therapy on the extension of experimentally induced peri-implantitis lesions.

Objectives: To investigate the extension of experimentally induced peri-implantitis lesions under various antiresorptive and antiangiogenic medications.

Material And Methods: Fourty-eight albino rats had randomly received the following medications (dual application, n = 8 each): (1) amino-bisphosphonate (zoledronate) (Zo), (2) RANKL inhibitor (denosumab) (De), (3) antiangiogenic (bevacizumab) (Be), (4) Zo+Be, (5) De+Be, or (6) no medication (Co). Ligature- and lipopolysaccharide-induced peri-implantitis lesions were established at 2 maxillary implants over a period of 16 weeks.

Efficacy of rehabilitation with different approaches of implant-supported full-arch prosthetic designs: A systematic review.

Aim: To evaluate the efficacy of different types of rehabilitation with fixed or removable full-arch implant-supported prosthesis designs in terms of implant loss and success in patients with at least one edentulous jaw, with tooth loss mainly due to periodontitis.

Materials And Methods: Clinical studies with at least 12 months reporting on implant loss and implant success were searched. Meta-analysis was conducted to estimate cumulative implant loss considering different prostheses designs.