Publications by authors named "Fanxuan Zhang"
Article Synopsis
- The study investigates the potential of sarsasapogenin (SAR) to promote bone and blood vessel formation in postmenopausal osteoporosis, which is linked to estrogen deficiency and ferroptosis.
- SAR shows promise in enhancing cell survival and bone development while reducing cell death in tests with stem cells and blood vessel cells.
- Results indicate that SAR activates a signaling pathway involving SLIT3 and ROBO1, which is crucial for coupling bone growth and blood vessel formation, with GPX4 playing a key role in this process.
Ethnopharmacological Relevance: Yunvjian decoction (YNJ) is a traditional Chinese herbal prescription that has been used in the clinical treatment of periodontitis. However, the underlying molecular mechanism of YNJ in the periodontitis treatment is not well understood.
Aim Of The Study: The purpose of this study was to evaluate the therapeutic effects of YNJ against periodontitis and its underlying molecular mechanisms.