Publications by authors named "Fanting Wang"
Background: DNA methylation catalyzed by various DNA methyltransferases (DNA MTases) is one of the important epigenetic regulations in both eukaryotes and prokaryotes. Therefore, the detection of DNA MTase activity is a vital target and direction in the study of methylation-related diseases.
Results: In this study, an ultrasensitive and robust strategy was developed for DNA MTase activity sensing based on bifunctional probe propelling multipath strand displacement amplification and CRISPR/Cas12a techniques.
Article Synopsis
- * This paper reviews various detection strategies for GMREs, focusing on methods like immunohistochemistry, fluorescence, and electrochemistry, among others.
- * It also discusses the use of novel nanomaterials and signal amplification techniques, aiming to identify challenges in GMRE detection and improve future diagnostic approaches.