Extraction, purification, structural characterization and biological activity of polysaccharides from Fritillaria: A review.

Fritillaria is a traditional Chinese medicine(TCM) with a history of thousands of years. Fritillaria always contain saponins, alkaloids, amino acids, flavones, and polysaccharides. Among them, Fritillaria polysaccharide has a variety of biological activities.

Simultaneous Determination and Pharmacokinetics Study of Three Triterpenes from L. in Rats by UHPLC-MS/MS.

A selective and rapid ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) method was established and validated for the determination of ziyuglycoside I, 3,19-dihydroxyurs-12-en-28-oic-acid 28--d-glucopyranosyl ester, and pomolic acid in rats after the oral administration of ziyuglycoside I, 3,19-dihydroxyurs-12-en-28-oic-acid 28--d-glucopyranosyl ester, pomolic acid, and L. extract. The separation was carried out on an ACQUITY UPLCHSS T column (2.

Biotransformation and pharmacokinetic studies of four alkaloids from Uncaria rhynchophylla in rat plasma by ultra-performance liquid chromatography with tandem mass spectrometry.

Uncaria rhynchophylla (Miq.) Miq. ex Havil (U.

Determination of Triterpenoids and Phenolic Acids from L. by HPLC-ELSD and Its Application.

A novel analytical method involving high-performance liquid chromatography with evaporative light scattering detection (HPLC-ELSD) was developed for simultaneous determination of 11 phenolic acids and 12 triterpenes in L. Chromatographic separation was conducted with gradient elution mode by using a Diamonsil C column (250 mm × 4.6 mm, 5 μm) with the mobile phase of 0.