Publications by authors named "Fanqian Yin"

Adaptation to high-altitude hypoxia is characterized by systemic and organ-specific metabolic changes. This study investigates whether intestinal metabolic rewiring is a contributing factor to hypoxia adaptation. We conducted a longitudinal analysis over 108 days, with seven time points, examining fecal metabolomic data from a cohort of 46 healthy male adults traveling from Chongqing (a.

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Article Synopsis
  • Scientists are studying how the bacteria in our gut react when people go to high places where there’s less oxygen, like mountains.
  • They took a long look at 45 healthy people who traveled from a low area to a high plateau for 108 days and found that their gut bacteria changed a lot, especially a type called Blautia A.
  • The study suggests Blautia A could help keep our guts healthy and help people adapt to living in places with less oxygen.
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Telomere is a unique DNA-protein complex which covers the ends of chromosomes to avoid end fusion and maintain the stability and integrity of chromosomes. Telomere length (TL) shortening has been linked to aging and various age-related diseases in humans. Here we recruited a total of 1031 Chinese individuals aged between 12 and 111 years, including 108 families with parents and their offspring.

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Polyploidization occurs widely in eukaryotes, and especially in plants. Polyploid plants and some fishes have been commercialized. Typically, severe genomic perturbations immediately follow polyploidization and little is known about how polyploid offspring survives the genetic and epigenetic changes.

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