Publications by authors named "Fanpan Du"

Lanbuzheng (LBZ) is the traditional seedling medicine in Guizhou, which has the effect of tonifying blood. It has been found that the main active ingredient is tannin, however, the blood-replenishing effect of tannin and its mechanism are still unclear. The study was to explore the mechanisms underlying the therapeutic effects of the total Tannins of Lanbuzheng (LBZT) against anemia in mice.

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Hair follicle development and hair growth are regulated by multiple factors and multiple signalling pathways. The hair follicle, as an important skin appendage, is the basis for hair growth, and it has the functions of safeguarding the body, perceiving the environment and regulating body temperature. Hair growth undergoes a regular hair cycle, including anagen, catagen and telogen.

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Article Synopsis
  • Acute UV-B radiation causes significant photodamage to cells, and the study focuses on how polysaccharides from Lindl. (DNPs) can help protect HaCaT keratinocytes from this harm.
  • DNPs were found to enhance cell viability and proliferation after UVB exposure by scavenging harmful reactive oxygen species, boosting antioxidant enzyme activities, and reducing malondialdehyde levels.
  • The protective effects of DNPs involve regulating specific signaling pathways that prevent cell cycle arrest and apoptosis, suggesting their potential as therapeutic agents against UVB-induced damage.
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Hair serves important physiological functions, including temperature regulation and scalp protection. However, excessive shedding not only impacts these functions but can also significantly affect mental health and quality of life. Tianma Gouteng decoction (TGD) is a traditional Chinese medicine used for the treatment of various conditions, including hair loss.

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