Merkel Cell Carcinoma Mimicking a Pyogenic Granuloma on the Thumb.

Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer that can present with various clinical manifestations. An 80-year-old male, known to have chronic lymphocytic leukaemia presented with a lesion on his left thumb, initially thought to be a pyogenic granuloma. The lesion was cauterized with silver nitrate but remained persistent.

Nose-to-brain delivery of chrysin transfersomal and composite vesicles in doxorubicin-induced cognitive impairment in rats: Insights on formulation, oxidative stress and TLR4/NF-kB/NLRP3 pathways.

Many cancer survivors suffer from chemotherapy-induced cognitive impairment known as 'Chemobrain'. Doxorubicin -topoisomerase II inhibitor- is widely used in breast cancer, hematological cancers and other neoplasms. However, it is reported to precipitate cognitive impairment in cancer patients via inducing oxidative stress and inflammatory response.

Teaching life cycle assessment in higher education.

Purpose: Scientific Life Cycle Assessment (LCA) literature provides some examples of LCA teaching in higher education, but not a structured overview of LCA teaching contents and related competencies. Hence this paper aims at assessing and highlighting trends in LCA learning outcomes, teaching approaches and developed content used to equip graduates for their future professional practices in sustainability.

Methods: Based on a literature review on teaching LCA in higher education and a collaborative consensus building approach through expert group panel discussions, an overview of LCA learning and competency levels with related teaching contents and corresponding workload is developed.

Patella Height in Different Ethnic Populations: An Observational Multicenter Study.

Patella height appears to have a crucial role in knee biomechanics. Patellar malalignment and maltracking are therefore believed to be associated with development and progression of patellofemoral pain and disease. Published data are scant regarding the effect of everyday tasks on patella height and patellofemoral disease.

Hip fracture litigation: A 10-year review of NHS Litigation Authority data and the effect of national guidelines.

We present a review evaluating all litigation claims relating to hip fractures made in a 10-year period between 2005 and 2015. Data was obtained from the NHS Litigation Authority through a freedom of information request. All claims relating to hip fractures were reviewed.

Adult respiratory distress syndrome.

Adult respiratory distress syndrome (ARDS) has now been described as a sequela to such diverse conditions as burns, amniotic fluid embolism, acute pancreatitis, trauma, sepsis and damage as a result of elective surgery in general. Patients with ARDS require immediate intubation, with the average patient now being ventilated for between 8 and 11 days. While the acute management of ARDS is conducted by the critical care team, almost any surgical patient can be affected by the condition and we believe that it is important that a broader spectrum of hospital doctors gain an understanding of the nature of the pathology and its current treatment.

Severe metallosis following polyethylene dislocation in a mobile-bearing medial unicompartmental knee replacement.

Metallosis is a rare cause of failure after unicompartmental knee replacement (UKR) and has only previously been reported when there has been abnormal metal-on-metal contact. We present a case report of a 67-year-old woman who was admitted to our department with a 5-month history of a painful right knee. There was no history of trauma and her past medical history was unremarkable.

Minimally invasive arthrodesis of the first metatarsophalangeal joint for hallux rigidus.

Background: First metatarsophalangeal joint arthrodesis plays a significant role in the management of symptomatic hallux rigidus. Several open and one percutaneous technique have been described in the literature. The authors present a minimally invasive technique, not previously published in the UK with patient-reported outcomes.

Primary renal embryonal rhabdomyosarcoma in adults: a case report and review of the literature.

Adult renal rhabdomyosarcoma is a rare subtype of renal sarcoma. We present a case of a renal mass treated with radical nephrectomy that subsequently was shown to be renal rhabdomyosarcoma. We discuss the clinical presentation, imaging findings, and histology for this case and review the available literature.

Image quality and radiation dose of pulmonary CT angiography performed using 100 and 120 kVp.

Objective: The objective of our study was to compare image quality and radiation dose of pulmonary CT angiography (CTA) performed in the same patient cohort using tube potentials of 100 and 120 kVp.

Materials And Methods: The study group for this retrospective study was 32 patients (22 women, 10 men) with a mean age of 57 years (age range, 28-83 years; body weight < 100 kg). Patients underwent pulmonary CTA studies performed using 120 and 100 kVp while other scanning parameters were kept constant.

Guide to surgical procedures on hollow viscera: part 2--Colorectal, ostomy, and malabsorptive bariatric procedures.

Objective: The objective of this article is to explore with a surgical perspective the key radiologic features of common bariatric, colorectal, and ostomy procedures. The images and diagrams show relevant postoperative anatomy.

Conclusion: An understanding of procedures on the hollow viscera is essential for a radiologist at any level.

Guide to surgical procedures on hollow viscera: part 1--Esophageal, gastric, and restrictive bariatric procedures.

Objective: The objective of this article is to explore with a surgical perspective the key radiologic features after common esophageal, gastric, and bariatric procedures.

Conclusion: An understanding of procedures on the hollow viscera is essential for radiologists at any level. The ability to quickly recognize postoperative anatomy is critical to accurately and efficiently interpret routine imaging studies and to diagnose postoperative complications.

Practices of Lebanese gynecologists regarding treatment of recurrent vulvovaginal candidiasis.

Background: A review of the literature clearly indicates the absence of one set of guideline in the treatment of recurrent vulvovaginal candidiasis. In Lebanon, as physicians are trained in European or American schools of medicine, locally or abroad, they may be approaching the issue of recurrent vulvovaginal candidiasis using various methods.

Aims: A national survey was conducted among Lebanese gynecologists to assess therapeutic protocols most commonly adopted to treat recurrent vulvovaginal candidiasis.

Pictorial essay: the value of rectal water in the assessment of rectosigmoid pathology.

The rectosigmoid region is a common location for the development of both malignant and benign diseases of the large bowel in adults. In many cases, rectal water provides an ideal contrast agent in the evaluation of rectosigmoid pathology. It allows optimal visualization of the mural layers and pericolic fat, as well as superior detection of flat or small sessile mural-based intralumenal filling defects.

Quantitative assessment of the superior sagittal sinus on unenhanced computed tomography.

Purpose: To determine the relationship between hemoglobin levels and attenuation measurements of the superior sagittal sinus (SSS) on unenhanced computed tomography (UECT). Secondly, to determine if SSS attenuation values are normally distributed such that measurements below and above certain thresholds are suggestive of pathology, such as anemia or acute venous thrombosis respectively.

Methods: Institutional review board approval was obtained for retrospective review of adult patients having both an UECT head examination and a complete blood count within 24 h of the scan.

Perivascular spaces: normal and giant.

The purpose of this paper is to discuss both normal perivascular spaces (PVSs) and pathological giant perivascular spaces (GPVSs). The anatomy and physiology of normal PVSs, including important immunological and lymphatic roles, are described. Special attention is given to the Magnetic Resonance Imaging (MRI) findings of both normal and GPVSs.

The effect of citrus limonoids on hamster buccal pouch carcinogenesis.

Two citrus limonoids, limonin and nomilin, were tested for their effects on the development of 7,12-dimethylbenz[a]anthracene (DMBA)-induced buccal pouch epidermoid carcinomas. Forty-five female Syrian hamsters were divided into three equal groups. The left buccal pouches of the animals in each group were pretreated topically with two applications of dimethylsulfoxide (DMSO) (group I), a 2.