Helminth/tuberculosis (TB) coinfection can weaken the immune response to Mycobacterium tuberculosis (Mtb) and worsen disease severity, with effects varying by helminth species.
The BCG vaccine for TB is currently available but has inconsistent effectiveness in preventing TB and its transmission.
Recent findings show that TB patients with helminth coinfection may experience increased Mtb-specific antibody responses, but the precise impact of different helminth species on this humoral response remains unclear, necessitating further research.