Publications by authors named "Fanny Josan"
Article Synopsis
- - The study investigates the role of miRNAs in the seminal plasma extracellular vesicles (SP-EVs) from high-fertile (HF) and low-fertile (LF) Sahiwal bulls, focusing on how these molecules might affect fertility through genetic and molecular signaling.
- - SP-EVs were isolated and analyzed, showing different sizes and particle concentrations between HF and LF bulls, but the overall differences in size and concentration were not statistically significant.
- - High-throughput miRNA sequencing identified 310 miRNAs, with significant differences in expression levels between HF and LF bulls, particularly highlighting bta-miR-195, which was found to be highly expressed in HF spermatozoa and may be linked to improved fertility
Backgroud: Before fertilization, spermatozoa undergo a crucial maturation step called capacitation, which is a unique event regulates the sperm's ability for successful fertilization. The capacitation process takes place as the spermatozoa pass through the female reproductive tract (FRT). Dihydrolipoamide dehydrogenase (DLD) protein is a post-pyruvate metabolic enzyme, exhibiting reactive oxygen species (ROS) production which causes capacitation.
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