Publications by authors named "Fanni S Kalman"
The aims and purposes of this systematic review of the international literature are to discuss and clarify some considerations on Burning Mouth Syndrome (BMS). Over the last 40 years, many researchers have addressed this disease clinically or experimentally. Thus, the etiology and pathogenesis of BMS remain unclear.
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- NADH cytochrome b5 oxidoreductase (Ncb5or) is crucial for protecting β-cells from oxidative stress, and its absence in lean mice leads to insulin-dependent diabetes due to β-cell death.
- The study investigates how certain natural missense mutations in the human NCB5OR gene affect protein expression, specifically focusing on two mutations (p.E87G and p.E93G).
- Results show that these mutations significantly decrease Ncb5or protein levels by increasing its degradation, suggesting they could have important implications for human diabetes and related health issues.
Redox state of pyridine nucleotides of the endoplasmic reticulum (ER) lumen was determined in different nutritional conditions. NADPH-dependent cortisone reduction and NADP(+)-dependent cortisol oxidation were measured in rat liver microsomes, by utilizing the luminal 11β-hydroxysteroid dehydrogenase type 1 activity. Cortisone reduction decreased, while cortisol oxidation increased during onward starvation, showing that the luminal NADPH/NADP(+) ratio was substantially decreased.
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