Background: Besides intraocular pressure, vascular factors play a role in the pathogenesis of glaucomatous optic neuropathy. One of these potential vascular factors is Flammer syndrome. The purpose of the present study was to determine in a Korean population whether signs and symptoms of Flammer syndrome occur more often in normal tension glaucoma patients than in control subjects.
View Article and Find Full Text PDFTechnol Health Care
September 2016
Photothermal treatment of tumors of the retina and choroid such as retinoblastomas, malignant melanomas, benign tumors as well as of vascular malformations can be performed by using laser radiation. A number of basic physical laws have to be taken into account in this procedure. Of particular importance thereby are: Arrhenius' law to approximate the kinetics of protein denaturation and photocoagulation, furthermore the electromagnetic radiation field, the distribution of both radiant and thermal energy induced in tumors and vascular structures, the influence of the wavelength and laser pulse duration (exposure time), as well as of the optical properties of the tissue.
View Article and Find Full Text PDFPurpose: Photon-correlation spectroscopy (PCS) (quasi-elastic light scattering spectroscopy, dynamic light scattering spectroscopy) allows the non-invasively reveal of local dynamics and local heterogeneities of macromolecular systems. The capability of this technique to diagnose the retinal pathologies by in-vivo investigations of spatial anomalies of retinas displaying non-exudative senile macular degeneration was evaluated. Further, the potential use of the technique for the diagnosis of the macular degeneration was analyzed and displayed by the Receiver Operating Curve (ROC).
View Article and Find Full Text PDFBackground: Autologous platelet-rich plasma (PRP) has been widely used for the treatment of sports injuries. It has been associated with improved healing and regeneration of soft tissues in elite athletes. Athletes are commonly receiving nonsteroidal anti-inflammatory drugs (NSAIDs).
View Article and Find Full Text PDFPurpose: The depth of corneal crosslinking (CXL) does not seem homogeneous within the treatment area but shows a reduction toward the periphery of the cornea. This study was undertaken to investigate this reduction effect and to look for possible solutions.
Methods: Ten corneas were investigated by means of an optical coherence tomography system (SS-100; Tomey, Nagoya, Japan) 1 month after standard CXL (epithelium off, 0.
Background: Probiotics are an upcoming group of nutraceuticals claiming positive effects on athlete's gut health, redox biology and immunity but there is lack of evidence to support these statements.
Methods: We conducted a randomized, double-blinded, placebo controlled trial to observe effects of probiotic supplementation on markers of intestinal barrier, oxidation and inflammation, at rest and after intense exercise. 23 trained men received multi-species probiotics (1010 CFU/day, Ecologic®Performance or OMNi-BiOTiC®POWER, n = 11) or placebo (n = 12) for 14 weeks and performed an intense cycle ergometry over 90 minutes at baseline and after 14 weeks.
Purpose: To explore the molecular alterations of the vitreous by dynamic light scattering (DLS) spectroscopy (quasi-elastic light scattering spectroscopy, photon-correlation spectroscopy) in normals and in patients afflicted with various degrees of non-proliferative and with proliferative diabetic retinopathy.
Methods: Dynamic light scattering spectroscopy was employed to analyze the vitreous of normals and of patients with diabetes non-invasively to estimate both the sizes and diffusion coefficients of mobile macromolecules and/or microparticles.
Results: Abnormal molecular behaviour of vitreous molecules was observed in patients with diabetes afflicted with various degrees of diabetic vitreo-retinopathy.
To help elucidate the interplay of physical forces, in particular pressure and flow, controlling the distribution and absorption of aqueous humor in subconjunctival tissue, a recently published computational model was considered where the fluid production in the eye, its removal via the trabecular/uveoscleral pathways and a surgical pathway are taken into account. The target quantity is the intraocular pressure. The surgical outflow pathway is linked to a fluid bleb that is positioned below the subconjunctival tissue and is modeled as a porous medium.
View Article and Find Full Text PDFPlatelet-rich plasma (PRP) has been employed to treat sports injuries to possibly accelerate healing and regeneration. This method offers some potential, especially for athletes. Growth factors are generally prohibited by the World Anti Doping Agency with exception to PRP which may induce adverse effects.
View Article and Find Full Text PDFA novel approach for applanation-free femtosecond refractive surgery with the help of a contact liquid layer is presented. A laboratory device for performing corneal procedures is described based on a femtosecond-laser system which has been tested and evaluated by processing ex vivo pig eyes. With its help, flap cuttings for different flap thicknesses were performed.
View Article and Find Full Text PDFPlatelet-rich plasma (PRP) to increase levels of platelets and growth factors has been used for the treatment of sports injuries suggesting to improve healing and regeneration. This method offers some potential especially for elite athletes. However, the insulin like growth factor-1 (IGF-1) is prohibited by the World Anti Doping Agency and, in addition, there may be a possible link between increased levels of IGF-1 and cancer risk.
View Article and Find Full Text PDFWe have investigated the nonlinear refractive index of ex-vivo pig cornea by a combined approach using the standard z-scan technique on extracted corneas or corneal slices, as well as studying the deviations caused by self-focusing during femtosecond laser processing of the pig eyes. The experiments yield consistently an upper limit of 1.2 MW for the critical power of self-focusing in porcine cornea, and a value of 2 x 10(-19) m(2)/W for its nonlinear refractive index.
View Article and Find Full Text PDFDynamic light scattering (DLS) measures the oscillations of macromolecules (MM) (Brownian motion). Small MM move fast, large MM slowly. DLS allows one to measure the relaxation of the movements of these MM, together with their sizes and their hydrodynamic diffusion coefficients.
View Article and Find Full Text PDFVernier thresholds rise much more rapidly in the periphery than do grating thresholds. A similar dissociation between acuity and hyperacuity has been shown to be present in strabismic but not in anisometropic amblyopia, thus leading to the suggestion that the strabismic fovea is similar to the normal periphery. Here it is shown that a quantitative model for spatial pattern discrimination, which accounts for foveal hyperacuity data, can be extended to encompass both the periphery and amblyopia if appropriate alterations are made.
View Article and Find Full Text PDFAn analysis and mathematical comparison of models underlying the phenomena of brightness and contrast are presented. The concept of self-excitation which has not so far been considered is introduced into the structure of the models. Mach Bands can be described by two essentially different but formally identical mechanisms.
View Article and Find Full Text PDFScand J Med Sci Sports
April 2009
We investigated competitive- and long-term oxidative stress during a competition season in eight top-ranked members of the Austrian Men's Alpine Ski Team. Serum total peroxides, antibody titers against oxidized LDL (oLAb) and lag time of the degradation of the fluorophore 1-palmitoyl-2-((2-(4-(6-phenyl-trans-1,3,5-hexatrienyl)phenyl)ethyl)-carbonyl)-sn-glycero-3-phosphocholine were measured, along with plasma concentrations of ascorbate, alpha- and gamma-tocopherol, beta-carotene, uric acid and the lipid status. Competitive stress was indicated through an increased post-race uric acid level (286 +/- 50 microM pre-race vs 456 +/- 77 microM post-race, P<0.
View Article and Find Full Text PDFObjective: To detect post-op molecular changes and inflammatory processes by dynamic light scattering (DLS) in eye segments. To develop DLS parameters which are appropriate for the control of post-op course after ophthalmologic surgery. METHODS, DESIGN: Three new DLS devices were tested in different post-op clinical settings such as pseudoexfoliation syndrome (PEX), cataract surgery and retinal surgery.
View Article and Find Full Text PDFTechnol Health Care
October 2007
Objective: To calibrate new dynamic light scattering (DLS) devices in defined solutions and post mortem porcine and human eyes. To examine all segments of the eye and to become familiar with the usage of the technique in living subjects. METHODS, DESIGN: Three new DLS devices for the usage in patients were developed.
View Article and Find Full Text PDFKlin Monbl Augenheilkd
August 2006
Background: At the present time, positive, wide-angle contact (and preset) lenses, having a large field of view, are widely used for inspecting and irradiating the fundus. They provide a real, inverted image of the fundus, but illuminate only the slit projected. The wide-field they provide (125 degrees ) is considered to be an advantage, but their image inversion and the lack of illumination of the whole field is disadvantageous.
View Article and Find Full Text PDFStudy Design: Prospective, nonrandomized, observational cohort study.
Objectives: To determine whether the presence of spinal cord hemorrhage and length of hematoma on magnetic resonance imaging (MRI) is predictive of recovery in cervical spinal cord injury (SCI).
Summary Of Background Data: A clear picture of the location, extent, and severity of traumatic cervical cord injury can be obtained with MRI.
Clin Orthop Relat Res
April 2006
Unlabelled: Proximal tibia fractures present a difficult treatment challenge with historically high complication rates. In a prospective study, we asked whether the Less Invasive Stabilization System (LISS) plate can adequately treat extraarticular and complex intraarticular proximal tibia fractures and provide low complication rates and acceptable long-term functional outcomes. We prospectively observed 25 patients with 26 proximal tibia fractures (AO type A2, A3, C1, C2, or C3) treated with the LISS.
View Article and Find Full Text PDFThe program Perisim 2000 enables one to simulate the interaction of a number of visual field examination strategies with a number of stored visual fields, both normal and pathological, with several patterns of observer (patient) behavior. A considerable number of visual fields, patient behavior patterns and examination strategies, including a full bracketing strategy, Gonzalez de la Rosa's tendency-oriented perimetry (TOP) and Weber's dynamic program, are available. Statistical programs are also incorporated.
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