Site-Specific Profiling of -Glycans in .

Background: is a well-studied and highly tractable genetic model system for deciphering the molecular mechanisms underlying various biological processes. Although being one of the most critical post-translational modifications of proteins, the understanding of glycosylation in is still lagging behind compared with that of other model organisms.

Methods: In this study, we systematically investigated the site-specific -glycan profile of using intact glycopeptide analysis technique.

Direct access to carbamates acylation of arylamines with dialkyl azodicarboxylates under metal-free conditions.

A novel C-N coupling of various arylamines with dialkyl azodicarboxylates under metal-free conditions for the rapid assembly of carbamates has been achieved. This established protocol features mild reaction conditions, simple operation, broad substrate scope, moderate to excellent yields and good tolerance of functional groups. Moreover, the potential synthetic utility of products was exemplified by a series of intriguing chemical operations.

Recent Advances in the Synthesis of 3,n-Fused Tricyclic Indole Skeletons via Palladium-Catalyzed Domino Reactions.

3,n-fused ( = 4-7) tricyclic indoles are pervasive motifs, embedded in a variety of biologically active molecules and natural products. Thus, numerous catalytic methods have been developed for the synthesis of these skeletons over the past few decades. In particular, palladium-catalyzed transformations have received much attention in recent years.

Thermal treatment's enhancement on high solid anaerobic digestion: effects of temperature and reaction time.

The methane production rate of high solid anaerobic digestion (HSAD) was poor although it was a promising technology with the advantages of small reactor, low energy consumption, and less digestate. In our research before, thermal treatment was proved to enhance HSAD's methane production rate via both batch experiments and continuous experiments of swine manure. However, the effect or investigation of thermal treatment's temperature-time combinations was not yet reported.